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Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Which combination of characteristics accurately describes Helicobacter pylori's morphology, growth conditions, and biochemical properties? (p 258)

a)

Non-motile, grows in 24–48 hours, urease negative, oxidase negative.

b)

Multiple polar flagella, urease positive, oxidase and catalase positive.

c)

Single flagellum, grows only in anaerobic conditions, urease positive, oxidase negative.

d)

Non-motile, colonies are opaque, requires rich media with no antibiotics for culture.

2.

The Vibrio cholerae factor responsible for diarrhea is a toxin that (p 260)

a)

Blocks EF-2

b)

Yields increased intracellular levels of cAMP

c)

Cleaves SNARE

d)

Blocks EF-1-dependent binding of amino-acyl-tRNA to ribosomes

3.

Which organism causes red tides and produces toxins harmful to humans? (p 7)

a)

Cyanobacteria

b)

Brown algae

c)

Green algae

d)

Dinoflagellates

4.

A 16-year-old female patient presented to her family physician with a complaint of an abnormal vaginal discharge and pruritus (itching). The patient denied having sexual activity and recently completed a course of doxycycline for the treatment of her acne. An examination of a Gram-stained vaginal smear revealed the presence of gram-positive oval cells about 4–8 µm in diameter. Her vaginitis is caused by which of the following agents? (p9)

a)

Bacterium

b)

Virus

c)

Protozoa

d)

Fungus

5.

What does Gram-staining mainly differentiate bacteria based on? (p 38)

a)

The type of DNA they have

b)

The thickness of their cell wall

c)

The way they move

d)

The toxins they produce

6.

Which of the following is not considered as a potential agent of bioterrorism and biologic warfare? (p279)

a)

Yersinia pestis

b)

Botulinum toxin

c)

Streptococcus pyogenes

d)

Brucella species

7.

A previously healthy 23-year-old woman recently returned from her vacation after visiting friends in Arizona. She complained of severe headaches, saw “flashing lights,” and had a purulent nasal discharge. She was admitted into the hospital with a diagnosis of bacterial meningitis and died 5 days later. Which of the following parasites should have been considered in the diagnosis? She had no prior history of travel outside of the United States. (Jawetz Microbiology, p 738)

a)

Plasmodium falciparum

b)

Toxoplasma gondii

c)

Strongyloides stercoralis

d)

Naegleria fowleri

8.

A Tzanck smear of a scraping obtained from a vesicle on the skin demonstrates multinucleated giant cells. Multinucleated giant cells are associated with which of the following viruses? (p 480)

a)

Varicella-zoster

b)

Variola major

c)

Coxsackievirus

d)

Molluscumcontagiosum

9.

An 8-year-old boy develops a circular dry, scaly, and pruritic lesion on his leg. What is the diagnostic significance of observing branching, septate, nonpigmented hyphae in a potassium hydroxide/calcofluor white preparation of a scraping from this skin lesion? (p 701)

a)

Chromomycosis

b)

Dermatophytosis

c)

Phaeohyphomycosis

d)

Sporotrichosis

10.

A 40-year-old man has HIV/AIDS characterized by a low CD4 count and a high viral load. Highly active antiretroviral therapy (HAART) will be initiated. One of the drugs under consideration is a nucleoside analog that inhibits viral reverse transcriptase and is active against both HIV and hepatitis B virus. That drug is (Harrisons Internal Medicine, p 438)

a)

Acyclovir

b)

Amantadine

c)

Ribavirin

d)

Lamivudine

11.

Which of the following immunoglobulin classes is the most abundant immunoglobulin in newborns?

a)

IgA

b)

IgE

c)

IgG

d)

IgM

12.

Which of the following immunoglobulins, if detected in a newborn, is most indicative of an intrauterine infection?

a)

IgA

b)

IgE

c)

IgG

d)

IgM

13.

Which pathogen is most frequently identified in cases of Brodie abscess?

a)

Staphylococcus aureus

b)

Pseudomonas aeruginosa

c)

Klebsiella spp.

d)

Streptococcus pyogenes

14.

What is the overall most common cause of osteomyelitis?

a)

Staphylococcus aureus

b)

Neisseria gonorrhoeae

c)

Streptococcus pyogenes

15.

Which of the following toxins is an important virulence factor in CA-MRSA?

a)

Panton-Valentine Leukocidin

b)

Hyaluronidase

c)

Clumping factor

d)

Hemolysin