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WorksheetsBIOCHEMISTRY PART 1
Total questions: 90
Worksheet time: 46mins
The type of transport when Ca ion is translocated by a Ca-pump is known as:
Symport
Antiport
Solubility dependent
Uniport
Concentration dependent
When blood glucose enters the cell, it will be phosphorylated to from glucose 6-P. this means that a phosphate group binds to:
Aldehyde on C number 1
Aldehyde on C number 6
Hydroxyl on C number 1
Hydroxyl on C number 6
Each C from 1 to 6
During fasting, the body relies on energy obtained from the hydrolysis of:
Glycogen
Polypeptide
Triacylglycerol
Cellulose
Amylum
Glut 4 is a glucose transporter that transfers glucose into:
Heart
Liver
Erythrocyte
Muscle
Brain
Biotin works as a coenzyme in the process of:
Methylation
Carboxylation
Hydroxylation
Oxidation
Decarboxylation
A sprinter has finished running 100 m in less than 10 seconds. The process to obtain energy was:
Aerobic with hydrolysis of high energy phosphates
Anaerobic through the respiratory chain
Aerobic with hydrolysis of creatine phosphate
Aerobic through the respiratory chain
Anaerobic with hydrolysis of high energy phosphates
Which of the following isn’t a property of biomembrane?
Constant
Dynamic
Fluid
Bilayer
asymmetric
When optimum temperature of enzyme is 40 C, what do you expect of its condition at 0 C?
Destroyed because of dehydration
Conserved and can be reactivated
Destroyed because enzyme is frozen
Conserved but type of reaction has changed
Destroyed because of denaturation
Transportation of glucose by GLUT (Glucose transporter) is classified as:
Active transport
Ca-cotransport
Facilitated diffusion
Ca-antiport
Simple diffusion
Cholesterol molecules give some strength to biomembranes but also serve to:
Limit water entering cell
Transport glucose into cell
Increase fluidity
Decrease oxidative stress
Transport Na into cell
Fusion of vesicle with membrane is found as a way of transport mechanism in:
Ca-pump
Intestinal mucosa
Nerve synapse
Glut 1
Na,K-pump
Humans are heteroph and the source of energy is basically …
Solar
Water
Plant
Animal
Seaweed
Glucose absorption from intestinal mucosa is mostly coupled with the ion:
Na+
H+
K+
Mg2+
Ca2+
The strength of erythrocyte membrane to undergo cell deformability when passing through capillaries, depends very much on the role of:
Membrane cholesterol
Cytoskeleton
Chloride transporter
Glucose transporter
Membrane protein
Cells of the intestinal mucosa are interconnected by:
Tight junction
Spot desmosome
Belt desmosome
Gap junction
Loose junction
Energy obtained from food consumption is released in the body as:
Heat
ATP and water
ATP, heat and water
ATP
ATP and heat
When physical activity is gradually increasing, the body starts using energy obtained from the catabolism of …
Amylum
Cellulose
Glycogen
Polypeptide
Triacylglycerol
ATP is a general source of energy in the body. The monosaccharide residue in ATP molecule comes from:
Deoxyribose
Ribose
Galactose
Glucose
Fructose
A good model represent the lock and key theory is the activity of …
Urease on urea
Pepsin on protein
Amylase on amylum
Lipase on fat
Dehydrogenase on alcohol
Biomolecules of the plasma membrane that are located extracellularly and not found on other parts of the cellular membrane are made up of …
Protein
Carbohydrate
Cholesterol
Phospholipid
Fatty acid
The biomolecules in biomembranes that function for transport, signalling and other functional activities are made of:
Phospholipid
Cholesterol
Triacylglycerol
Protein
Carbohydrate
The kind of transport system when extrusion of 3 Na is accompanied by 2 K entering the cell can be found as a case of:
Facilitated antiport
Gradient driven transport
Facilitated symport
Active antiport
Active symport
ATP activates glucose by releasing one phosphate group to be attached on the glucose molecule. The enzyme doing this activity is glucokinase classified as:
Transferase
Oxidoreductase
Isomerase
Hydrolase
Ligase
Carbohydrate in membrane is one of the factors that causes asymmetry since carbohydrate:
Prefers facing the intracellular fluid
Is most present sticking out of the outer membrane layer
Must be part of a liposaccharide
Is connected with hydrophobic membrane center
Is present as the smallest amount of biomolecules
The smallest group of biomolecules in biomembrane consists of…
Carbohydrate
Glycolipid
Phospholipid
Cholesterol
Protein
The destructive action of free radicals can be inhibited by:
Hydrolase
Dehydrogenase
Oxygenase
Superoxide dismutase
Catalase
Brown fat plays an important role for babies because it:
Contains high content of mitochondria to provide energy for growth
Provides insulation for organs
Provides lubrication for joints
Contains high content of mitochondria capable of uncoupling process
Provides fatty acids for synthesis of tissue fat
Fat is chemically a triacylglycerol. This means that fat molecule contains 3 bonds of:
Nucleotide
Ether
Ester
Glyceride
Peptide
Fluidity and flexibility of biomembranes increase with increasing membrane content of:
Unsaturated fatty acids
Cholesterol
Glycolipid
Triacylglycerol
Saturated fatty acids
The density of biomembrane is determined by its content of:
Phospholipid
Protein
Carbohydrate
Glycolipid
Cholesterol
In case of competitive enzyme inhibition, the competing compounds to occupy the active site are:
Coenzyme and product
Coenzyme and inhibitor
Substrate and inhibitor
Product and inhibitor
Substrate and coenzyme
Biochemical reactions in the body proceed lifelong at a normal temperature of 36.5 C isothermically. The system that makes this possible is primarily:
Enzyme
Body water
Energy
Glucose easily dissolves in water because it contains many groups of:
Carbonyl
Aldehyde
Sulfhydryl
Carboxyl
Hydroxyl
CO is fatally toxic since it can inhibit:
Cytochrome oxidase
ATP synthase
NAD dehydrogenase
Succinate dehydrogenase
ATP transferase
Ether used in anesthesia is a diethylether, meaning that the molecule is made up of 2 ethyl groups connected by:
–O–
–NH–
–S–
–S–S–
–C–
Coupling reactions always lose some energy that cannot be utilized. Fate of this energy is:
Absorbed by tissues
Converted to ATP
Converted to heat
Conserved by the body
Converted to water
A double bonded oxygen at the end of a carbon chain is found in the molecular structure of a:
Ether
Acid
Aldehyde
Ester
Ketone
The lipid mostly found in myelin sheath of nerves is:
Phospholipid
Cholesterol
Sphingolipid
Fatty acid
Triacylglycerol
Conjugation of 2 molecules means uniting two groups of the molecules to form a bigger one with the release of:
CO2
H2S
H2
H2O
NH3
A special and unique characteristic feature that is found in enzymes but not found in inorganic catalysts is:
Resistant to high temperature
Only active for a specific reaction
Soluble in lipid solution
Only active at low pH
Low molecular weight
Detoxification through hydroxylation is carried out by:
Oxidase
Catalase
Oxygenase
Superoxide dismutase
Hydrolase
Simple diffusion is a membrane transport mechanism that:
Is driven by ATP as source of energy
Moves particles from high to low concentration
Applies only to absorption by the intestinal wall
Does not apply to gas particles
Is good to translocate large molecules
O2 can diffuse through the membrane of alveoli and the endothelium of capillary blood vessel because of:
The high affinity of O2 to oxygen carrier within erythrocyte
The difference of partial pressure of O2 within alveoli and blood
The molecular weight of O2 molecule which is very small
The solubility of O2 in the blood
The affinity of O2 with the protein in the blood
Which of the following enzymes related to digestion is secreted by salivary gland?
Trypsin
Enterokinase
Lactase
Pepsin
Amylase
The purpose of metabolism of xenobiotics is:
To increase their fat solubility
To decrease their pH
To increase their surface tension
To decrease their affinity to protein
To increase their water solubility
The main lipid component of the lung surfactant is:
Cholesterol
Dipalmitoyl lecithin
Triacylglycerol
Arachidonic acid
Sphingomelyn
Hepatic disease leads to major elevation of the blood level of which one of the following substances?
Heme
Bile acid
Conjugated bilirubin
Biliverdin
Unconjugated bilirubin
Which one of the following organs is most involved in the metabolism of xenobiotics?
Lung
Kidney
Lymphoid glands
Liver
Spleen
Which one of the following organs secretes cholesterol esterase?
Stomach
Pancreas
Spleen
Liver
Gall bladder
Insulin hormone contains two polypeptide chains that are linked together through which kind of bonding?
Disulfide
Glycoside
Hydrogen
Peptide
Ester
The chloride shift is the exchange of chloride ion with
CO2
O2
Bicarbonate ion
Na ion
K ion
Which one of the following organs synthesizes enterokinase?
Intestine
Gall bladder
Liver
Kidney
Pancreas
Hypoventilation is physiological mechanism to:
Lower [CO2] in the blood and increase blood pH
Raise [CO2] in the blood and decrease blood pH
Lower [CO2] in the blood and decrease blood pH
Raise [CO2] in the blood and increase blood pH
Lower [CO2] in the blood and increase blood pH
Most of water from the consumed food is absorbed in the:
Duodenum
Ileum
Gaster
Colon
Jejunum
A 38 year old women is found to have an obstructing gallstone in the common bile duct. What is the impact of this condition?
Increased recycling of bile salts
Increased absorption of cholesterol from the intestine
Decreased excretion of protein in the feces
Increased digestion of carbohydrate in the intestine
Increased excretion of fat in the feces
Vitamin B6 deficiency would be expected to result in the inhibition of:
Porphobilinogen deaminase
ALA synthase
Uroporphyrinogen decarboxylase
ALA dehydrates
Ferrochelatase
The major mechanism of reaction in phase 1 of metabolism of xenobiotics is:
Conjugation
Hydroxylation
Carboxylation
Oxidation
Deamination
Ammonia in colon is the product of putrefaction and fermentation by microorganism from:
Protein
Strach
Triacylglycerol
Cholesterol
Fatty acid
Which statement is true concerning the intestinal brush border membrane?
Alpha amylase is secreted by brush border membrane
Enterokinase is required for the absorption of glucose
Sucrase is only found in the brush border membrane
Maltose crosses the brush border membrane
Bile salt is required for the absorption of glucose
The normal pH of the blood occurs if the ratio [BHCO3] and [H2CO3] is:
15
20
5
10
25
One of the characteristics of porphyrin is:
It is a hemoprotein
Is is an amphoter
It contains Zn
It is a colorless substance
It is a component of vitamin B1
Which of the following organs is the site of procarboxypeptidase synthesis?
Liver
Stomach
Pancreas
Gallbladder
Spleen
In what state are saturated fatty acids found at room temperature?
Gas
Vapour
Liquid
Solids
Condensed
Biosynthesis of heme requires which on of the following substances?
Glutamic acid
Propionyl CoA
Succinyl CoA
Ferric ion
Acetyl CoA
Mostly digestive products are processed through a metabolic pathway into a common product, namely:
Pyruvic acid
Glucose 6-phosphate
ATP
Acetyl-CoA
Fructose 6-phosphate
Which of the following enzymes has autocatalytic characteristic?
Pepsin
Lipase
Amylase
Cholesterol esterase
Enterokinase
UDP glucuronyltransferase participates in the conjugation process of bilirubin in order to make it:
Water soluble and directly enter the blood system
Less soluble in water for easy storage in gall bladder
Less soluble in water to protect from oxidation
Water soluble and secreted into the bile
Water soluble and directly secreted into the intestinum
Which of the following substances is the substrate of lipase?
Arachidonate
Palmitate
Prostaglandin
Cholesterol
Triacylglycerol
Complex lipids with fatty acid components that bind to sugar are called:
Glycolipid
Glycerophospholipid
Sphingolipid
Glucosan
Amylopectin
Why is hydrochloric acid secretion within the stomach important in digestion?
It is required for the activity of alpha-amylase
It drives secondary active transport of amino acid
It converts pepsinogen to pepsin
It is required for lipid digestion
It stimulates the cleavage of trypsinogen to trypsin
Which of the following substances related to digestion is secreted by liver?
Biliverdin
Bilirubin
Bicarbonate
Lipase
Bile acid
Which of the following cases of acid-base imbalance is present in patients with renal failure?
Metabolic acidosis
Respiratory alkalosis
Metabolic alkalosis
Respiratory acidosis
Metabolic alkalosis hypokalemia
Which one of the following enzymes contains iron porphyrin?
Carbonic anhydrase
Ferrochelatase
Peroxidase
Carboxypeptidase
Glutaminase
Metabolic acidosis occurs in:
Bronchitis
Pneumonia
Asthma bronchiale
Cushing syndrome
Severe diarrhea
Which of the following acid-base imbalance is present in patients with uncontrolled diabetes mellitus?
Respiratoric alkalosis
Metabolic alkalosis with hypokalemia
Metabolic acidosis
Respiratoric acidosis
Metabolic alkalosis
Edema can occur in hypoalbuminemia which is a complication of:
Lung disease
Severe diarrhea
Liver disease
Heart disease
Severe vomiting
The mechanism of reaction in phase 2 of metabolism of xenobiotics is:
Hydrolysis
Conjugation
Dehydrogenation
Decarboxylation
Reduction
Aldose is referred to as a reducing sugar. This means that aldehydes are capable to be oxidized forming:
R-CHO
R-COOH
R-CO
R-O-R
R-OH
The regulatory enzyme of the biosynthesis of porphyrin is:
Protoporphyrinogen oxidase
Uroporphyrinogen decarboxylase
ALA synthase
Porphobilinogen deaminase
ALA dehydratase
During a breathing cycle:
Gas exchange between the alveoli and the capillary blood can occur at all times
Atmospheric water vapour is taken up by the lung
There is net uptake of nitrogen by the blood
The alveolar gases are completely exchanged for atmospheric gases
Gas exchange with the capillary blood occurs at the surface of all the airways
The normal color of feces is due to which one of the following substances?
Stercobilin
Biliverdin
Bilirubin
Cholesterol
Bile acid
What is the normal range of the blood’s pH?
7.50 – 7.43
7.23 – 7.45
7.25 – 7.50
7.48 – 7.25
7.35 – 7.45
The main buffer system in erythrocyte is:
H2CO3 – BHCO3 buffer system
Lactate buffer system
Phosphate buffer system
Albumin buffer system
Hemoglobin buffer system
The process of chloride shift occurs in:
The wall of alveoli
The membrane of erythrocyte
The membrane of leucocyte
The membrane of enterocyte
The membrane of blood vessel
The concentration of protein human in human. Plasma is important in determining the distribution fluid between blood and tissue. The major protein in human plasma is:
Laminin
Albumin
Alpha globulin
Gamma globulin
Beta globulin
Which of the following organs are important in regulating the pH of the blood?
Liver and spleen
Kidney and lung
Kidney and liver
Lung and liver
Liver and muscles
Proteins are linear heteropolymers of α-amino acids. Alpha carbonof amino acids is carbon number?
2
3
5
4
1
Hepatic disease leads to major elevation of the blood level of
Bile acid
Biliverdin
Cholesterol
Conjugated bilirubin
Unconjugated bilirubin
Which one of the following substances is strong acid?
Lactic acid
Hydrochloric acid
Carbonic acid
Acetic acid
Phosphoric acid
Which of the following organs has no role in digestion
Stomach
Pancreas
Liver
Mouth
Spleen
