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Genomics Worksheet

Total questions: 30

Worksheet time: 15mins

Name
Class
Date
1.

Where would you find your DNA?

a)

In all of the cells in your body

b)

In most of the cells in your body

c)

In none of the cells in your body

2.

What are genes?

a)

Specific sections of DNA

b)

All the DNA in your cells

c)

Energy providers for the cell

3.

What is a chromosome?

a)

A tightly bundled molecule of DNA

b)

A type of brightly coloured enzyme

c)

Where proteins are made

d)

The centre...

4.

How many chromosomes do most human cells contain?

a)

23

b)

46

c)

92

5.

Genetics is the study of all an individual's DNA.

a)

True

b)

False

6.

What is a genome (gee-nome)?

a)

A garden ornament

b)

An organism’s complete genetic material

c)

A group of genes

7.

Approximately how many protein-coding genes does the human genome have?

a)

20,000

b)

200,000

c)

2,000,000

8.

How much of your genome contains the instructions to produce proteins?

a)

2%

b)

32%

c)

82%

9.

How much of your genome is the same as everyone else’s genome?

a)

1%

b)

50%

c)

99.9%

10.

Some people have a perfect genome.

a)

True

b)

False

11.

Why do people want to study the genome?

a)

Scientific research

b)

Specific health reasons

c)

Trace ancestry

d)

...

12.

In healthcare, the 0.1% variation in our genome can tell us whether someone: Choose the correct option(s).

a)

Will develop a condition

b)

Is more susceptible to a condition

c)

Their reaction to different drugs

13.

To investigate an individual's genome, we need a sample of their DNA. Name at least two types of material that we can obtain DNA from.

a)

Hair roots, skin cells, bone marrow

b)

Saliva, tears, sweat

c)

Nail clippings, earwax, blood plasma

d)

Urine, bile, stomach acid

14.

What is genomic sequencing?

a)

Creating new DNA in a lab

b)

Reading an individual's genome

c)

Putting DNA together

15.

Now that we’ve read the human genome, we know everything about it.

a)

True

b)

False

16.

What term is used to describe the passing down of genetic information?

a)

Inherited

b)

Trait

c)

Identity

17.

Cancer is a disease of the genome.

a)

True

b)

False

18.

Which of these are genetically inherited conditions?

a)

Cystic fibrosis

b)

Tuberculosis

c)

Huntington disease

19.

Only humans have a genome.

a)

True

b)

False

20.

Antibiotic resistance is linked to genomics.

a)

Yes

b)

No

21.

Genomics is used in infectious disease outbreaks.

a)

True

b)

False

22.

The size of a change in our genome is directly linked to the potential impact it has on health.

a)

Yes

b)

No

23.

Two patients have the same genetic changes that are known to be disease-causing. It is inevitable that they will present with the same symptoms.

a)

True

b)

False

24.

A patient’s genomic information is the only factor considered for personalised medicine.

a)

True

b)

False

25.

What is pharmacogenomics?

a)

A. A type of gene therapy

b)

B. [Option not visible]

c)

C. Genomic information can be used to tailor pharmaceutical therapies to suit each individual. The way our bodies respond to some drugs depends on our unique genome.

26.

In a clinical context, what is a family history?

a)

Health information of an individual and their closest relatives

b)

A doctor’s photo

27.

A patient is worried their family has an inherited condition. What could be an appropriate first action?

a)

Draw a genetic pedigree

b)

...

28.

Angelina Jolie chose to have a double mastectomy based on a genetic diagnosis.

a)

True

b)

False

29.

What does the word ‘familial’ in ‘familial breast cancer’ mean?

a)

The condition is related to diet

b)

The condition occurs within a family or its members

30.

An individual has bowel cancer. What would sequencing the tumour genome tell us?

a)

If the cancer was inherited

b)

The type of bowel cancer

c)

The stage of the cancer

d)

Potential treatments for the cancer