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MicroPhysio (during #1)

Total questions: 110

Worksheet time: 2hrs 37mins

Name
Class
Date
1.

which statement is true about archaeal CW?

a)

Glycan units are connected by beta-1,4 bonds

b)

peptide bridge contains L-amino acids

c)

glycan units consist of NAM acid

d)

None of the above

2.

in the transpeptidation reaction of the peptidoglycan synthesis in Gram(-) bacteria, the displaced amino acid is ?

(a)  

3.

All are components of a Gram(-) CW except:

a)

lipid a

b)

teichoic acids

c)

PG layer

d)

DAP acid

4.

which is not a characteristic of the PG layer?

a)

the repeating unit is called the glycan tetrapeptide

b)

the glucose residues are connected by beta-1,4 linkages

c)

is a disaccharide polymer

d)

is a soluble and porous polymer

5.

what is the function of the intracytoplasmic membrane in Rhodopseudomonas palustris?

a)

stores ions

b)

involved in septum formation

c)

involved in CW formation

d)

increases the surface area for energy transduction

6.

which statement is not true regarding the composition of phospholipids in the CM?

a)

the phosphatidylglycerol component is formed from equimolar ratios of G3P and FAs

b)

lipids associated with the CM are structurally symmetrical

c)

the FA composition depends on species and environmental conditions

d)

all statements are true

7.

which statement is not true regarding the bacterial CM?

a)

the non-polar FA regions interact with each other via hydrogen bonding

b)

the polar region interacts with cations and water via ionic interactions

c)

the glycerol backbone of the phospholipid is connected to a phosphate group via a covalent bond

d)

the hydrophobic side chain is connected to glycerol by ether linkages

8.

which statement is not true about the assembly of CM proteins?

a)

CM proteins are produced by cytosolic ribosomes

b)

a signal peptide is required at the amino terminus

c)

proteins pass through across the PM using the translocase

d)

SecA binds to unfolded preprotein

9.

all statements are true regarding FA biosynthesis during membrane synthesis except:

a)

ATP is required

b)

acetyl-CoA must be converted to malonyl-CoA to initiate

c)

biotin carboxylase and carboxyl transferase are required for the rx to proceed

d)

bactoprenol plays a key role

10.

in the type iv pilus, which protein has an ATPase function for pilus assembly and extension?

(a)  

11.

what is the function of the mesosome?

a)

involved in septum formation

b)

involved in DNA replication

c)

involved in CW formation

d)

all of the aforementioned

12.

what is the function of sulfur globules?

a)

floatation

b)

reserve energy source

c)

light-harvesting pigment

d)

site of CO2 fixation

13.

all characteristics of gas vesicles except:

a)

permeable to water

b)

are small, cylindrical structures composed of a single small protein

c)

freely permeable to gases

d)

the alpha-helix structure, GvpC, is responsible for cross-linking

14.

which is not true about fimbriae and pili?

a)

all of the choices

b)

pili are longer protein appendages for surface attachment

c)

fimbriae are short, bristle-like proteins around the cell

d)

fimbriae and pili structures are distinct from one another

15.

immediate precursor of lysine in bacterial CW for bacterial biosynthesis of an amino acid

(a)  

16.

negatively charged so generally responsible for the whole cell surface charge. it is also highly antigenic and facilitates the attachment of bacteriophages

(a)  

17.

teichoic acid is composed of these compounds with attached molecules of glucose or D-Ala. ___ and ___

(a)  

18.

it extends all the way to the CM and is covalently linked, linear polymers of 16-40 phosphodiester-linked glycerophosphate residues.

(a)  

19.

composed of alternating repeats of glucose residues, which is also called murein. it is a big, insoluble, porous polymer

(a)  

20.

glucose residues of bacterial peptidoglycan (do not abbreviate)

(a)  

21.

glycosidic linkage of bacterial peptidoglycan

(a)  

22.

during biosynthesis, it carries the PG precursors through the cell membrane

(a)  

23.

an enzyme that destroys the old beta-1,4 bonds to attach new NAM-NAG precursors.

(a)  

24.

is a transpeptidase that catalyzes the formation of cross-bridges and synthesis in bacterial CW peptidoglycan

(a)  

25.

substance that binds to D-ala-D-ala terminal of PG precursors; prevents cross-linking

(a)  

26.

substance that inhibits transpeptidase, preventing cross-linking. it is especially true in Gram(+) bacteria but has a weak penetration in Gram(-) bacteria due to its selective permeability.

(a)  

27.

substance that has the same function as Penicillin but it is especially effective against Pseudomonas aeruginosa and some Proteus species

(a)  

28.

substance that inhibits Alanine racemase and D-ala-D-ala dipeptide during the cytoplasmic stage

(a)  

29.

a composition of the Gram-positive CW that is an acidic polysaccharide containing uronic acids

(a)  

30.

what are the four compositions of the outer membrane of a Gram-negative bacterial CW

(a)  

31.

an endotoxin of the Gram-negative bacterial CW that is an effective barrier against many substances that may penetrate the CM

(a)  

32.

is a short polysaccharide of the OM consisting of peculiar sugars that varies between bacterial strains (sugars: glucose, galactose, rhamnose, mannose, dideoxyhexose)

(a)  

33.

FAs bonded through the amine groups from a disaccharide composed of glucosamine phosphate linked by beta-1,6 bonds. it also helps in avoidance of host defenses.

(a)  

34.

it mediates interconnection between the OM and murein

(a)  

35.

an aqueous component between the cell membrane and OM in Gram-negative bacteria

(a)  

36.

it is a component of the periplasm that degrade nutrients to smaller molecules that can be transported across the membrane by specific transporter

(a)  

37.

a component of the periplasm involved in the osmotic regulation of the periplasm because their amounts decrease when the cells are grown in media of high osmolarity

(a)  

38.

a component of the periplasm that is required for the uptake of several solutes that do not diffuse through the porin.

(a)  

39.

are integral membrane proteins in the CW of Gram(-) bacteria. composed of beta-barrel architecture with short loops between strands on the periplasmic side and large, extended loops on the extracellular side. (three words; do not abbreviate)

(a)  

40.

is a protein porin specific for maltose and maltodextrin. it is a receptor for bacteriophage lambda.

(a)  

41.

it is a major OMPs for structural support and cell adhesion in Gram(-) bacteria.

(a)  

42.

they are mostly in Gram(-) bacteria that forms small hydrophilic channels through the outer envelpoe allowing the passive diffusion of neutral and charged (<600 Daltons) solutes of MW.

(a)  

43.

it consist of interlocking molecules of proteins or glycoproteins of the archaeal CW, sometimes with COOH attached. sufficiently strong to withstand osmotic pressure alone.

(a)  

44.

consists of glycan units NAG and NAT, linked by beta-1,3 glycosidic bonds, and has L-amino acids peptide bridge.

(a)  

45.

cell wall profile/s of Methanocaldococcus jannaschii. (do not abbreviate)

(a)  

46.

cell wall profile/s of Thermoplasma. (do not abbreviate)

(a)  

47.

a class of small cell wall-less bacteria that possesses distinct morphologies.

(a)  

48.

the additional layer in the CM of Mollicutes.

(a)  

49.

its major functions are: selective permeability, protein anchor, and energy conservation and consumption

(a)  

50.

in Eukaryotic cells, where does energy conservation for respiration takes place?

(a)  

51.

in Eukaryotic cells, where does energy conservation for photosynthesis takes place?

(a)  

52.

what do you call the hydrophobic tail of the lipid monolayer in Archaea?

(a)  

53.

the linkage between the hydrophobic tail and hydrophilic head in Bacteria and Eukarya?

(a)  

54.

the linkage between the hydrophobic tail and hydrophilic head in Archaea?

(a)  

55.

the archaeol analogue of phosphatidylethanolamine

(a)  

56.

what enzymes do bacteria do not possess when it cannot carry out stage 1 of glycolysis?

(a)  

57.

A series of enzymatic reactions in glycolysis converting glucose to pyruvate. (pathway)

(a)  

58.

What is the primary end product of the Embden-Meyerhoff-Parnas Pathway?

(a)  

59.

True or false: The EMP pathway occurs in the cytoplasm of cells.

a)

TRUE

b)

FALSE

60.

It acts as an electron carrier, becoming NADH during glycolysis.

(a)  

61.

A process where ATP is produced directly from a substrate during glycolysis.

(a)  

62.

How many ATP molecules are generated in glycolysis?

(a)  

63.

True or false: Glycolysis is an anaerobic process.

a)

TRUE

b)

FALSE

64.

What is the initial substrate for the Embden-Meyerhoff-Parnas Pathway?

(a)  

65.

In the first step in glycolysis involves the phosphorylation of glucose to form (a)   .

66.

What enzyme catalyzes the conversion of glucose to glucose-6-phosphate?

(a)  

67.

What enzyme catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconolactone?

(a)  

68.

The anaerobic catabolism that follows glycolysis, regenerating NAD+. In this process, the organic compound is both an electron donor and an electron acceptor.

(a)  

69.

Pyruvate is converted to ___ or ___ during fermentation.

(a)  

70.

True or false: The Embden-Meyerhoff-Parnas Pathway is part of cellular respiration.

a)

TRUE

b)

FALSE

71.

What is the total yield of NADH from one glucose molecule in glycolysis?

(a)  

72.

A metabolic pathway that generates NADPH and pentoses from glucose-6-phosphate, and generates reducing equivalents for reductive biosynthesis reactions within the cells.

(a)  

73.

A molecule in PPP that provides reducing power for biosynthetic reactions.

(a)  

74.

True or false: The Pentose Phosphate Pathway occurs in the cytosol.

a)

TRUE

b)

FALSE

75.

Fill in the blank: The Pentose Phosphate Pathway is also known as the (a)   pathway.

76.

A pentose sugar produced in the non-oxidative phase of the pathway.

(a)  

77.

What is produced during the oxidative phase of the Pentose Phosphate Pathway?

(a)  

78.

A five-carbon sugar molecule important in nucleic acid structure.

(a)  

79.

Fill in the blank: Transaldolase and transketolase are enzymes in the (a)   phase.

80.

True or false: The Pentose Phosphate Pathway is not involved in fatty acid synthesis.

a)

TRUE

b)

FALSE

81.

What are the end products of the non-oxidative phase?

(a)  

82.

A metabolic pathway that is unique in prokaryotes, especially in Gram(-) bacteria. It may be used to catabolize gluconate or gluconic acid.

(a)  

83.

True or false: The Entner-Duodoroff Pathway is more efficient than glycolysis.

a)

TRUE

b)

FALSE

84.

What are the end products of the Entner-Duodoroff Pathway?

(a)  

85.

True or false: The Entner-Duodoroff Pathway occurs in the cytoplasm.

a)

TRUE

b)

FALSE

86.

True or false: The Entner-Duodoroff Pathway is an anaerobic process.

a)

TRUE

b)

FALSE

87.

A key intermediate in several metabolic pathways, including glycolysis.

(a)  

88.

a molecule in the EDP that is toxic for the cell, inhibits its growth

(a)  

89.

This species' sole pathway is anaerobic Entner-Duodoroff Pathway

(a)  

90.

The metabolic process of synthesizing glucose from non-carbohydrate precursors.

(a)  

91.

True or false: Gluconeogenesis occurs primarily in the liver.

a)

TRUE

b)

FALSE

92.

Which hormone stimulates gluconeogenesis?

(a)  

93.

A multi-enzyme complex that converts pyruvate into acetyl-CoA.

(a)  

94.

True or false: NAD+ is a cofactor for the pyruvate dehydrogenase complex.

a)

TRUE

b)

FALSE

95.

What are the three main components of the pyruvate dehydrogenase complex?

(a)  

96.

True or false: The pyruvate dehydrogenase complex requires oxygen to function.

a)

TRUE

b)

FALSE

97.

What is produced alongside acetyl-CoA by the pyruvate dehydrogenase complex?

(a)  

98.

What is produced alongside acetyl-CoA by the pyruvate dehydrogenase complex?

(a)  

99.

A cofactor that carries acetyl groups into the Krebs cycle, in the context of the pyruvate dehydrogenase complex.

(a)  

100.

it exerts feedback inhibition to phosphofructokinase

(a)  

101.

A reactive dicarbonyl compound involved in various metabolic pathways.

(a)  

102.

True or false: Methylglyoxal is a byproduct of glycolysis.

a)

TRUE

b)

FALSE

103.

How many turns of the Krebs cycle will each glucose molecule produce?

(a)  

104.

How many turns of the Krebs cycle will each glucose molecule produce?

(a)  

105.

In one turn of the cycle, how many of the products are formed?

a)

1 ATP, 3 NADH, 1 FADH2, 2 CO2

b)

1 ATP, 2 NADH, 2 FADH2, 1 CO2

c)

2 ATP, 3 NADH, 2 FADH2, 2 CO2

d)

2 ATP, 2 NADH, 1 FADH2, 1 CO2

106.

How does the Krebs cycle allow for ATP synthesis ?

a)

The rotation of the Krebs cycle turns a “rotor” in the cell to synthesize ATP

b)

ATP is synthesized by substrate level phosphorylation during the removal of the coenzyme A upon entrance into the cycle

c)

High energy electrons are stored in NADH and FADH2 to shuttle to the ETC to generate a proton gradient

d)

Krebs cycle completes the breakdown of glucose to release the energy and store it in the form of ATP

107.

The Krebs cycle requires oxygen, because..

a)

Without oxygen, glycolysis cannot take place to provide the starting materials for the Krebs cycle

b)

Without oxygen, ATP cannot be synthesized by substrate level phosphorylation

c)

Without oxygen, coenzyme A is unable to be added to the pyruvate molecule to make acetyl CoA

d)

Without oxygen NADH cannot be oxidized to continue receiving electrons as NAD+

108.

Which enzyme catalyzes the first step of the Krebs Cycle, where acetyl-CoA combines with oxaloacetate?

a)

Citrate synthase

b)

Aconitase

c)

Isocitrate dehydrogenase

d)

Succinate dehydrogenase

109.

In the Krebs Cycle, which molecule is directly involved in substrate-level phosphorylation to produce ATP?

a)

Citrate

b)

Succinate

c)

GTP

d)

Fumarate

110.

How many turns of the Krebs cycle per glucose molecule?

a)

1

b)

2

c)

3

d)

4