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WorksheetsQuiz on Hyperglycemia and Obesity
Total questions: 91
Worksheet time: 46mins
Stress hyperglycemia is primarily driven by which hormones?
Thyroid
Counter-regulatory
Gonadotropins
Mineralocorticoids
Counter-regulatory hormones in stress hyperglycemia include cortisol, catecholamines, glucagon and:
Prolactin
Melatonin
Growth hormone
Aldosterone
A key metabolic defect in stress hyperglycemia is:
Increased glucose utilization
Decreased lipolysis
Increased glucose production
Increased insulin secretion
Admission glucose ≥250 mg/dL in pneumonia increases mortality and:
Stroke
Arrhythmia
Hospital complications
Renal stones
Hyperglycemia (>200 mg/dL ×2) occurs in hospitalized patients in:
10%
20%
38%
75%
Newly discovered hyperglycemia is associated with:
Shorter stay
Lower ICU use
Longer hospital stay
Minimal impact
Hyperglycemia significantly increases risk of:
Viral infections
Fungal infections
Bacterial infections
Parasitic infections
Poor wound healing in hyperglycemia is largely due to impaired:
Lymphatics
Coagulation
Tissue perfusion
Bone turnover
Hospital hyperglycemia is strongly linked to which condition(s)?
Dementia
Osteoporosis
MI, Stroke, Trauma
IBS
Stress hyperglycemia vs. newly diagnosed diabetes can be differentiated by:
Electrolytes
CRP
HBA1c
Insulin level
NICE-SUGAR recommends glucose target in ICU:
80-110
100-130
140-180
200-250
Intensive insulin therapy increases:
Hypernatremia
Stroke
Hypoglycemia
Hyperkalemia
NICE-SUGAR showed higher 90-day mortality in:
Conventional therapy
Intensive therapy
Both equal
Not reported
AACE-ADA recommends insulin therapy when glucose exceeds:
120 mg/dL
150 mg/dL
180 mg/dL
250 mg/dL
Recommended ICU glucose target (AACE-ADA):
<110
110-140
140-180
>180
WHO defines obesity primarily as excess
Protein
Water
Fat
Bone
BMI obesity cutoff (WHO)
23
25
27
30
BMI obesity cutoff (Asian)
25
30
35
28
ABCD stands for Adiposity-Based
Cardiac Disease
Chronic Disease
Chemical Disorder
Cellular Dysfunction
Waist circumference is used to assess
Bone mass
Abdominal fat
Muscle mass
Hydration
Y-Y Paradox highlights mismatch between BMI and
Water
Fat %
Protein
Glycogen
Most accurate body composition method
Tape measure
DXA
Skinfolds
Impedance
ORCD stands for Obesity-Related
Cardiac Disorders
Complications & Diseases
Chronic Distress
Circulatory Deficit
Obesity complication: metabolic
Psoriasis
PCOS
COPD
Anxiety
For OA, required weight loss is around
5%
10%
20%
1%
Bariatric surgery typical weight loss
5%
10%
20-30%
40%
Pharmacotherapy expected loss
1%
3%
5-15%
30%
Most potent incretin for weight loss
Orlistat
Semaglutide
Metformin
Spironolactone
Tirzepatide mechanism
GLP-1 only
GIP only
GLP-1 + GIP
GLP-2
Mean weight loss with tirzepatide (obesity, no diabetes)
5%
9%
15-21%
30%
Retatrutide activates GLP-1, GIP and
Cortisol
Glucagon receptor
GH receptor
Leptin receptor
Orforglipron is the first oral non-peptide
DPP-4 inhibitor
GLP-1 agonist
Insulin mimetic
Lipase blocker
CagriSema combines semaglutide +
Orlistat
Cagrilintide
Phentermine
Lorcaserin
GLP-1 agonists reduce
MI risk
TSH
Sodium
Calcium
GLP-1 slows
Heart rate
Gastric emptying
Bone turnover
Muscle growth
BELIEVE trial combo was semaglutide +
Liraglutide
Bimagrumab
Metformin
Sitagliptin
Bimagrumab preserves
Fat
Lean mass
Water
Bone
Median diabetes-free survival after gastric bypass is:
3 years
5 years
8.3 years
12 years
Higher chance of diabetes remission is associated with:
Older age
Longer diabetes duration
Shorter diabetes duration
Insulin treatment
Higher visceral fat is linked with:
Better remission
Worse remission
No change
Higher cure rate
Perioperative mortality of metabolic surgery is:
0.01 %
0.1-0.5 %
1 %
5 %
Early dumping syndrome usually starts:
1-5 minutes
10-30 minutes
1 hour
3 hours
Late dumping syndrome usually starts:
10 minutes
20 minutes
1-3 hours
10 hours
Main driver of late post-surgical hypoglycemia is:
Slow carbohydrate absorption
Excess endogenous hormone surge
Low cortisol
Low insulin
Post-surgical hypoglycemia risk is highest after:
1 month
3 months
More than 1 year
10 years
First-line management of post-surgical hypoglycemia is:
Insulin
Carbohydrate reduction
Steroids
Glucagon
Substance use increases the risk of:
Rapid healing
Surgical complications
Iron overload
Bone pain
Substance use increases the risk of:
Rapid healing
Surgical complications
Iron overload
Bone pain
Surgery should be postponed in individuals with:
Mild anxiety
Active depression
Resolved psychiatric issues
Mild reflux
Hormone-based anti-obesity medications can be used:
Only before surgery
Only after surgery
Before or after surgery
Not at all
The only currently approved short-term weight-loss device is the gastric:
Band
Balloon
Suction tube
Stimulator
Five-year diabetes remission after gastric bypass is:
10 %
33.1 %
41.6 %
60 %
Five-year diabetes remission after sleeve gastrectomy is:
10 %
16.1 %
33 %
50 %
Hormone-based medications after surgery help treat:
Gastroparesis
Weight regain
Hypothyroidism
Vitamin deficiency
Micronutrient and metabolic monitoring after surgery should be:
None
Short-term
Long-term
Once yearly
Metabolic surgery should be performed in centers with:
Single surgeon
Interprofessional teams
Radiology only
Endocrinology only
Lifestyle medicine reverses which root driver?
Genetics
Behaviour
Infection
Autoimmunity
Early diabetes shows partial reversibility of which function?
Alpha cell
Beta cell
Delta cell
Liver cell
Post-meal walking reduces glucose peaks by:
Ten percent
Fifteen percent
Twenty to thirty percent
Forty percent
Minimum sleep linked with increased insulin resistance:
Four hours
Five hours
Six hours
Eight hours
Remission is improved most by reducing:
Hepatic glucose output
Platelet function
Protein intake
Sodium load
Diet trials showing forty-six percent remission at one year:
DPP
Look AHEAD
DIRECT
Finnish DPS
Most consistent guideline advice is to increase:
Meat
Fruits
Vegetables
Sugar
Ultra-processed foods mainly cause:
Low cortisol
Inflammation
Low insulin
Low glucose
Strongest contributor to hyperglycemia among substances:
Tobacco
Alcohol
Sugary drinks
Salt
Stress increases glucose via hormone:
Thyroxine
Cortisol
Aldosterone
Progesterone
Movement used as 'glucose disposal therapy':
Fasting
Post-meal walk
Yoga only
Swimming only
Most protective sleep target:
Four hours
Five hours
Seven to eight hours
Ten hours
Strong predictor of better adherence in diabetes:
Income
Social support
Marital status
Gender
Diet pattern rich in olive oil and fish:
Atkin
Mediterranean
Mind
Dash
Behavioural drivers of obesity best reversed by:
Surgery
Medication
Lifestyle
Supplements
Postural behaviour needing interruption every thirty minutes:
Running
Standing
Sitting
Sleeping
Limiting this fat improves insulin sensitivity:
Saturated fat
Poly fat
Mono fat
Omega fat
Most helpful proteins for glycemic control:
Red meat
Chicken
Fish
Cheese
Sleep disruption increases:
Glucose stability
Glucose variability
Ketone stability
Appetite loss
Emotional eating is strongly driven by:
Low oxygen
Stress
Sodium
Growth hormone
First-line intervention in type 2 diabetes?
Tablets
Lifestyle
Insulin
Surgery
Main cause of increased fasting glucose early in disease?
Low insulin
High glucagon
High fat
Low exercise
Drug group that lowers risk of heart failure admission?
Pioglitazone
Alpha blockers
SGLT2 inhibitors
Sulfonylurea
Drug class with weight loss benefit?
DPP4 inhibitors
GLP1 agonists
Sulfonylurea
Meglitinides
Drug class linked with weight gain?
Insulin
GLP1 agonists
SGLT2 inhibitors
Metformin
When to start dual therapy?
A1C under six
A1C under seven
A1C eight point five or more
A1C ten or more
Drug with strong kidney protection?
DPP4 inhibitors
Sulfonylurea
SGLT2 inhibitors
Insulin
Empagliflozin reduces death from heart causes by?
Ten percent
Twenty percent
Thirty-eight percent
Fifty percent
Empagliflozin reduces new or worsening kidney disease by?
Ten percent
Twenty percent
Thirty-nine percent
Fifty percent
Early disease stage with rising glucose post meals?
Normal
Prediabetes
Severe diabetes
Crisis
A one percent fall in A1C reduces stroke risk by?
Twelve percent
Thirty percent
Forty percent
Fifty percent
Cardiovascular guideline recommending risk-based drug choice?
ADA
EASD
ESC
WHO
Condition strongly linked with insulin resistance?
Migraine
Central obesity
Appendicitis
Asthma
Drug option for high cardiovascular risk?
Sulfonylurea
DPP4 inhibitors
SGLT2 inhibitors
Bromocriptine
Therapy recommended when A1C ten or more?
One tablet
Dual therapy
Insulin
Diet only
