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Test 5 pt 2

Total questions: 32

Worksheet time: 16mins

Name
Class
Date
1.

What type of bonding is responsible for maintaining the shape of the tRNA molecule?

a)

hydrogen bonding between base pairs

b)

peptide bonding between amino acids

c)

covalent bonding between sulfur atoms

d)

ionic bonding between phosphates

2.

Why don't highly specialized cells get cancer?

a)

They actually do, they just get it late in life.

b)

Highly specialized cells are missing the genes that create cancer.

c)

Highly specialized cells are unable to undergo mitosis.

d)

These cells only produce mutations in the germ-line cells.

3.

For a couple of decades, biologists knew the nucleus contained DNA and proteins. The prevailing opinion was that the genetic material was proteins, and not DNA. The reason for this belief was that proteins are more complex than DNA. This is most likely because...(common sense answer based on knowledge at the time)

a)

proteins have two different levels of structural organization; DNA has four.

b)

proteins are made of 20 amino acids and DNA is made of four nucleotides.

c)

all of the above are correct

d)

proteins have a greater variety of three-dimensional forms than does DNA.

4.

A frameshift mutation could result from:

a)

a base substitution only.

b)

a base insertion only.

c)

both a base insertion or a base deletion

d)

a base deletion only

5.

This is the mechanism that normally stops cells from forming tumors (cell piles).

a)

contact division

b)

cell-to-cell contact

c)

contact inhibition

d)

cell division

6.

What are ribosomes composed of?

a)

IRNA and proteins

b)

mRNA, IRNA, and proteins

c)

proteins only

d)

IRNA only

7.

The Y-shaped structure where the DNA double helix is actively unwound during DNA replication is called the:

a)

Y junction

b)

replication fork

c)

elongation point

d)

replication Y

8.

What is the function of DNA polymerase?

a)

to add nucleotides to the end of a growing DNA strand

b)

to rejoin the two DNA strands (one new and one old) after replication

c)

to unwind the DNA helix during replication

d)

to seal together the broken ends of DNA strands

9.

What does transformation involve in bacteria?

a)

the creation of a strand of DNA from an RNA molecule

b)

the type of semiconservative replication shown by DNA

c)

the infection of cells by a phage DNA molecule

d)

assimilation of external DNA into a cell

10.

During RNA processing a(n) __ is added to the 5' end of the RNA.

a)

3' untranslated region

b)

5' untranslated region

c)

coding segment

d)

a long string of adenine nucleotides

11.

What are the coding segments of a stretch of eukaryotic DNA called?

a)

transposons

b)

introns

c)

codons

d)

exons

12.

An insertion or deletion causes this effect on the genome:

a)

base substitution

b)

frame-shift mutation

c)

recombination

d)

point mutation

13.

What do Chargaff's rules state?

a)

the amount of A = T and the amount of G = C

b)

all of the above

c)

the amount of A & T, G & C will vary by species

d)

the bases will always exhibit complementary base pairing

14.

A particular eukaryotic protein is 300 amino acids long. Which of the following could be the maximum number of nucleotides in the DNA template strand that codes for the amino acids in this protein?

a)

100

b)

3

c)

900

d)

300

15.

Using RNA as a template for protein synthesis instead of translating protein directly from the DNA is advantageous for the cell because:

a)

Many tRNA molecules can be transcribed from multiple genes, increasing the potential rate of gene expression.

b)

all of the above are reasons

c)

RNA acts as an expendable copy of the genetic material, allowing the DNA to serve as a permanent, pristine repository of the genetic material.

d)

RNA is more stable than DNA.

16.

Each DNA strand is copied by the actions of an enzyme called:

a)

DNA polymerase

b)

DNA replicase

c)

DNA ligase

d)

DNA helicase

17.

In his work with pneumonia-causing bacteria and mice, Griffith found that:

a)

bacteriophages injected DNA into bacteria.

b)

heat-killed pathogenic cells caused pneumonia.

c)

some substance from pathogenic cells was transferred to non-pathogenic cells, making them pathogenic.

d)

the protein coat from pathogenic cells was able to transform non-pathogenic cells.

18.

After DNA replication is completed,

a)

each new DNA double helix consists of two new strands.

b)

each new DNA double helix consists of one old DNA strand and one new DNA strand

c)

each of the four DNA strands consists of some old strand parts and some new strand parts.

d)

one DNA double helix consists of two old strands and one DNA double helix consists of two new strands.

19.

Which of the following is a way to help prevent cancer?

a)

avoid smoking

b)

all of the above are ways to help prevent cancer

c)

avoid salted or smoked foods

d)

eat cabbage family vegetables

20.

A eukaryotic cell lacking active telomerase would:

a)

have a greater potential to become cancerous.

b)

be unable to identify and correct mismatched nucleotides.

c)

be unable to take up DNA from the surrounding solution.

d)

experience a gradual reduction of chromosome length with each replication cycle.

21.

From Rosalind Franklin's X-Ray diffraction data, which of the following was determined about DNA?

a)

All of these were determined.

b)

The molecules had two chains.

c)

The shape of the molecule could be a double helix.

d)

Nitrogenous bases were arranged on the inside of the structure.

22.

Why are hereditary forms of cancer so dangerous?

a)

it takes a long time to get all the necessary mutations

b)

you are automatically born with cancer

c)

a proper diet will not work to help prevent cancer

d)

all the vulnerable cells already have 1 of the 2 necessary mutations

23.

What are the non-coding segments of a stretch of eukaryotic DNA called?

a)

introns

b)

exons

c)

codons

d)

transposons

24.

You briefly expose bacteria undergoing DNA replication to radioactively labeled nucleotides. When you centrifuge the DNA isolated from the bacteria, the DNA separates into two classes. One class of labeled DNA includes very large molecules (thousands or even millions of nucleotides long), and the other includes short stretches of DNA (several hundred to a few thousand nucleotides in length). These two classes of DNA probably represent:

a)

leading strands and RNA primers.

b)

Okazaki fragments and RNA primers.

c)

lagging strands and Okazaki fragments.

d)

leading strands and Okazaki fragments.

25.

Which of the following mutations would be most likely to have a harmful effect on an organism?

a)

a base-pair substitution

b)

a deletion of three nucleotides near the middle of a gene

c)

a single nucleotide deletion near the end of the coding sequence

d)

a single nucleotide insertion downstream of, and close to, the start of the coding sequence

26.

Which of these is a difference between a DNA and an RNA molecule?

a)

DNA is double-stranded, whereas RNA is single-stranded.

b)

DNA contains uracil, whereas RNA contains thymine.

c)

DNA contains five-carbon sugars, whereas RNA contains six-carbon sugars.

d)

DNA is a polymer composed of nucleotides, whereas RNA is a polymer composed of nucleic acids.

27.

Translation occurs where in the cell?

a)

the nucleolus

b)

the cytoplasm

c)

a nucleoplasm

d)

the nucleus

28.

A silent mutation has what effect?

a)

it has no effect

b)

it moves all bases forward one, to make room for the new base

c)

it moves all bases backwards one, to fill in for the lost base

d)

it replaces a base, changing the genetic code at that codon

29.

What do Chargaff's rules state?

a)

the bases will always exhibit complementary base pairing

b)

the amount of A & T, G & C will vary by species

c)

the amount of A = T and the amount of G = C

d)

all of the above

30.

In order to get cancer, cells must...

a)

have 1 of the 2 possible mutations in their alleles already.

b)

be able to reproduce.

c)

be genetically predisposed to forming cancer.

d)

be visible to the sun's ultraviolet radiation.

31.

What is the effect of a nonsense mutation in a gene?

a)

It changes an amino acid in the encoded protein.

b)

It alters the reading frame of the mRNA.

c)

It has no effect on the amino acid sequence of the encoded protein.

d)

It introduces a stop codon into the mRNA.

32.

Once transcribed, eukaryotic mRNA typically undergoes substantial alteration that includes...

a)

fusion into circular forms known as plasmids.

b)

union with ribosomes.

c)

linkage to histone molecules.

d)

excision of introns.