Worksheetspneumotropic viral diseases
Total questions: 52
Worksheet time: 31mins
ACUTE
contagious disease of upper respiratory
Influenza
Influenza are
NOT the retrovirus
NOT the stomach flu
NOT an enveloped
NOT ssRNA
what are the characteristic of Influenza?
ssDNA
Enveloped
Non-enveloped
ssRNA
how is influenza transmitted?
divided into subtypes
infects humans, birds, pigs
Type A influenza
Type B influenza
Type C influenza
NO subtypes
infects humans
Type A influenza
Type B influenza
Type C influenza
rare, mild disease in humans
Type A influenza
Type B influenza
Type C influenza
which types raises more concerns about pandemics?
Type A influenza
Type B influenza
Type C influenza
Which are true about the viral envelope of Influenza?
has spikes
2 proteins
no spikes
2 proteins
has spikes
0 proteins
what are the two proteins found in Influenza?
Influenza protein that attach to host cell
has 16 different subtypes
Neuraminidase (N)
Hemagglutinin (H)
Amantadine (A)
Influenza protein that can entry or exit of virions in or out f host cell
has 9 different subtypes
Neuraminidase (N)
Hemagglutinin (H)
Amantadine (A)
Hemagglutinin (H) and Neuraminidase (N) are both antigenic meaning
Virions (infected virus form) constantly undergo _____ in H and N proteins.
genetic changes
characteristic
antigenic drift in influenza can look like
minor mutations
year-to-year variations
major mutations
some immunity from previous strain
no or little immunity
antigenic shift in influenza can look like
minor mutations
reassorments as virus crosses species
major mutations
some immunity from previous strain
no or little immunity
what is an example of Antigenic shift in influenza?
Small point mutations in HA/NA
H1N1 one year and H1N1 again
H2N3 mutates to H1N1
Manifestations of Influenza
increased body temp upto 40c
1-2 weeks complete resolution
long-lived
risk of secondary infections amongst old and young
what are serious complications of Influenza?
Guillain-Barre Syndrome (GBS)
Reye's syndrome
SARS CoV 2
Multiple Sclerosis
neurological symptoms
polio-like paralysis
usually reversible
Guillain-Barré Syndrome (GBS)
Reye's Syndrome
neurological symptoms
in children following flu or chicken pox
child experiences repeated vomiting, lethargy, disoriented, combativeness
Guillain-Barré Syndrome (GBS)
Reye's Syndrome
death rate of Influenza in North America
10,000 / year
20,000 / year
40,000 / year
90% of influenza deaths are ages
65 and older
8 and younger
75 and older
less then 2 years old
Influenza vaccine includes 3-6 strains of whole, destroyed virus
, which are are true about them
old prominent strains
new prominent strains
top 3 strains from last year
top 3 new strains
the flu shot this year 2025-2026 is called
Adjuvalent
Trivalent
Tamiflu
what's the effectiveness % of Influenza vaccine?
how is influenza vaccine USUALLY made?
K9 kidney cells
embryonated fish eggs
embryonated chicken eggs
can account for about 30% of all "common colds"
about 100 diff strains
mutate often
Adenoviruses
Rhinoviruses
what are the characteristic of Rhinovirus?
ssDNA
Enveloped
Non-enveloped
ssRNA
what are the characteristic of Rhinovirus?
ssDNA
Enveloped
Non-enveloped
ssRNA
what are the characteristic of Adenovirus?
ssDNA
Enveloped
Non-enveloped
ssRNA
dsDNA
accounts for 15% of common URT infections (common cold)
symptoms can be severe
Adenoviruses
Rhinoviruses
Adenoviruses severity can cause
ear infections
joint stiffness
aseptic meningitis
conjunctivitis (pink eye)
how does Adenovirus penetrate host?
viral RNA injected into nucleus of host cell for viral protein production
viral DNA injected into nucleus of host cell for viral protein production
Adenovirus is a good candidate for which therapy?
why is adenovirus a good candidate for gene therapy?
because it carry small RNA inserts
dsDNA or double gene disease
because attenuated virus is infectious but not contagious
dsDNA for gene insertion and protein production
what are the characteristic of SARS CoV 2?
ssDNA
Enveloped
Non-enveloped
ssRNA
dsDNA
SARS CoV 1 has ____ genetic similarity between SARS Cov 2 and bat coronavirus
80%
85.6%
72%
96.2%
which are true about mutation of SARS CoV 2 and WHY?
has a large genome
replication and mutation is faster than most human enveloped virus
replication and mutation is slower than most human enveloped virus
SARS CoV 2 targets which host receptor and why?
because it's found in URT
because it's found in LRT
symptoms of SARS CoV aside from cough, sore-throat, fever, myalgia, lethargy
shortness of breath
loss of smell/taste
joint stiffness
GI symptoms
corticosteroids is considered treatment for severe SARS CoV 2 because
Corticosteroids have anti-inflammatory action.
corticoids in SARS CoV patients have shown reduce death and hospitalization by
10-20 %
30-50 %
35-60 %
what are the characteristic of RSV or Respiratory Syncytial Virus?
ssDNA
Enveloped
Non-enveloped
ssRNA
dsDNA
typically affects children under 5
can cause runny nose, coughing, fever
SARS CoV 2
Respiratory Syncytial Virus / RSV
Influenza
Rhinovirus
Adenovirus
typically affects children under 5
can cause runny nose, coughing, fever
SARS CoV 2
Respiratory Syncytial Virus / RSV
Influenza
Rhinovirus
Adenovirus
Respiratory Syncytial Virus or RSV can progress to which conditions
why does RSV or Respiratory Syncytial Virus typically affects children under 5?
An approved vaccine for RSV is targeted for those who are
adults over 60
infants an and high risk children
what are the two major proteins on surface of RSV or Respiratory Syncytial Virus
G glycoprotein is to _____ where as F glycoprotein is to ______
on RSV or Respiratory Syncytial Virus
What are the pneumotropic viral diseases
SARS CoV 2
Respiratory Syncytial Virus / RSV
Influenza
Rhinovirus
Adenovirus
