NEW
Font size
WorksheetsGenetic 2
Total questions: 20
Worksheet time: 20mins
Which of the following syndromes is an example for deletion?
Turner syndrome
Down syndrome
Klinefelter syndrome
Cri-du-chat syndrome
Which of the following banding techniques is routinely used in chromosome analysis?
C-banding
T-banding
G-banding
R-banding
All are the features of Lyon's hypothesis except.,
Out of 2X chromosomes, one becomes inactive
Inactivation occurs after birth
Inactivation occurs in early embryonic life
Inactivated chromosomes maybe materially or paternalistic derived.
The karyotype of Klinefelter syndrome is
47 XXY
47 XXX
47 XYY
47 YYY
Trisomy 18 is
Down syndrome
Patau syndrome
Edward syndrome
Turner syndrome
Trisomy 21 is
Down sndrome
Edward syndrome
Patau syndrome
Turner syndrome
Which of the following is a structural chromosomal abnormality?
Trisomy 21
Monosomy X
Robertsonian translocation
Triploidy
A Barr body represents:
Inactivated X chromosome
All Y chromosomes
Extra autosome
Fragmented chromatin
The mechanism responsible for Down syndrome in most cases is:
Translocation
Isochromosome formation
Meiotic non-disjunction
Mitochondrial mutation
Klinefelter syndrome typically shows
One Barr body
No Barr body
Two Barr bodies
Mosaicism 47, XYY
According to Denver classification, Group A chromosomes are:
1–3
13–15
16–18
19–20
Which karyotype is seen in Down syndrome due to Robertsonian translocation?
46, XY, t(14;21)
47, XY
Trisomy 21
Mosaicism
A patient with short stature, webbed neck, and shield chest is most likely:
Klinefelter syndrome
Turner syndrome
Down syndrome
Patau syndrome
Which structure is most suitable for numerical chromosomal analysis?
Bone marrow
Buccal smear
Lymphocyte culture
Platelets
The phenomenon of failure of homologous chromosomes to separate in meiosis I is:
Non-disjunction
Duplication
Crossing over
Deletion
Which is a disadvantage of amniocentesis?
No fetal karyotype obtained
Increased risk of miscarriage
Cannot detect neural tube defects
Done too early
The law of segregation refers to separation of:
Traits
Gene pairs (alleles)
Chromatid pairs
Autosomes
Structural abnormality caused by breakage and reunion of nonhomologous chromosomes:
Deletion
Isochromosome
Translocation
Inversion
Presence of 2 Barr bodies indicates genotype:
47, XXX
45, X
46, XX
47, XXY
The Philadelphia chromosome involves a translocation between:
8 and 14
9 and 22
14 and 21
11 and 22
