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Worksheetsclass A2 exam
Total questions: 11
Worksheet time: 6mins
Which of the following enzymes is the key regulatory enzyme in heme synthesis?
Uroporphyrinogen III synthase
Porphobilinogen synthase
ALA synthase
Hydroxymethylbilane synthase
Uroporphyrinogen III decarboxylase
Which of the following is considered a high-grade lymphoma?
Small lymphocytic lymphoma
Marginal zone lymphoma
Mantle cell lymphoma
Diffuse large B-cell lymphoma
Hodgkin lymphoma
Iron is incorporated into protoporphyrin IX by which enzyme?
ALA dehydratase
Heme oxygenase
Porphobilinogen deaminase
Ferrochelatase
Heme decarboxylase
Which cell type is characteristic of nodular sclerosis Hodgkin lymphoma?
Mononuclear Reed-Sternberg cells
Lacunar Reed-Sternberg cells
L&H cells
Hallmark cells
Mummified cells
In heme synthesis, which enzyme is located in the mitochondria?
Porphobilinogen synthase
Hydroxymethylbilane synthase
Uroporphyrinogen III synthase
Uroporphyrinogen III decarboxylase
ALA synthase
Which of the following is a characteristic feature of Burkitt lymphoma?
Nodular growth pattern
Low mitotic activity
Small-sized transformed lymphocytes
L&H cells
Starry-sky appearance
The last step of heme synthesis is mediated by which enzyme?
Porphobilinogen deaminase
Heme oxygenase
ALA dehydratase
Ferrochelatase
Heme decarboxylase
Which immunohistochemical marker is characteristic of mantle cell lymphoma?
CD15
CD5 & CD23
C-MYC
Cyclin D1
CD10
Which condition results from deficiency of vitamin B12 or folic acid?
Hemolytic anemia
Aplastic anemia
Megaloblastic anemia
Blood loss anemia
What is the normal life span of an erythrocyte?
90 days
100 days
120 days
150 days
Where does erythropoiesis primarily occur in adults?
Liver
Spleen
Bone marrow of flat bones and ends of long bones
Lymph nodes
