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WorksheetsPathphysio 2 51-65
Total questions: 15
Worksheet time: 8mins
A female patient, age 45 years, had a biochemical blood test: Total protein 45 g/l, albumin 25 g/l, globulin 20 g/l, urea 5.5 mmol/l, creatinine 80 µmol/l, glucose 3.2 mmol/l, total bilirubin 50 µmol/l, Conjugated bilirubin 30 µmol/L, unconjugated bilirubin 20 µmol/L, total cholesterol 3.5 mmol/L, ALT 85 ME/L, AST 70 ME/L. Identify the most likely pathology in which this test might be?
parenchymatous jaundice
Hemolytic jaundice
mechanical jaundice
pancreatitis
dumping syndrome
A 35-year-old man complains of severe epigastric pain occurring 2-3 hours after meals and at night; recently, the pain has become accompanied by nausea and sometimes vomiting. There were two episodes of melena. X-ray examination reveals the 'niche' symptom. Laboratory examination: hemoglobin 90 g/l, erythrocytes 3.5x1012/l, leukocytes 8x109/l. Biopsy of the ulcer site: Helicobacter pylori +++. Gastric secretion analysis revealed increased levels of basal secretion, total acidity, free and bound HCI, and pepsin. Define the pathology most likely to develop in the patient?
cardia achalasia
acute pancreatitis
gastric ulcer
duodenal ulcer
chronic pancreatitis
A 35-year-old man complains of severe epigastric pain occurring 2-3 hours after meals and at night; recently, the pain has become accompanied by nausea and sometimes vomiting. There were two episodes of melena. A radiograph shows the 'niche' symptom. Laboratory examination: hemoglobin 90 g/l, erythrocytes 3.5x1012/l, leukocytes 8x109/l. Biopsy of the ulcer site: Helicobacter pylori +++. Analysis of gastric secretion revealed increased levels of basal secretion, total acidity, free and bound HCI, and pepsin. What is the most likely mechanism of ulcer formation under the influence of Helicobacter pylori?
prolonged spasm of blood vessels and muscles of the stomach and intestines
increased secretion and acidity of gastric juice
stimulation of gastric T-lymphocytes to damage epithelial cells
increased secretion of pepsinogen-1
increase in acid-aggressive activity of gastric juice
A patient with yellow skin staining has elevated levels of unconjugated bilirubin in the blood. What is the most likely cause of this pathology?
Hepatocyte damage by hepatitis A viruses
acute blood loss
Decreased osmotic resistance of erythrocytes
bile duct stones
gallbladder dyskinesia
5-year-old child has increased salivation, spitting, and maceration of the skin around the mouth. Which of the following is the most likely consequence of this pathology?
xerostomia
hypokalemia
multiple dental caries
oral mucosal atrophy
hyperacidity of gastric juice
A 45-year-old man complains of bloating, flatulence, and liquid stools. These symptoms appeared several months ago, occurring 30-60 minutes after breakfast. Every day he eats cereal with milk and yogurt for breakfast. Physical examination revealed no abnormalities. The patient was suggested to stop taking dairy products for 1 week. All his symptoms disappeared. What is the most likely cause of this pathology?
malabsorption syndrome
Galactose intolerance
Intestinal dysbacteriosis
chronic pancreatitis
depleted gastric acidity
A 65-year-old man has been diagnosed with a mechanical type of constipation. The patient most likely has diverticulosis of the colon
endocrine disorder
increased extraintestinal water loss
irritable bowel syndrome
decreased food intake
A 55-year-old woman with chronic hepatic insufficiency showed prolongation of prothrombin time, decreased prothrombin index with normal fibrinogen content and normal thrombin time. What is the leading factor in the pathogenesis of changes in the patient's hemostasis parameters?
deficiency of vitamin K-dependent clotting factors
dysfibrinogenemia
abundance of anticoagulants in the blood
An impairment of the internal prothrombinase activation mechanism
Disorder of external mechanism of prothrombinase activation
A 55-year-old man complains of bloating, emaciation, frequent diarrhea, and vomiting. The man abuses alcohol. Laboratory findings. Blood: hemoglobin 110 g/l, red blood cells 3.4x1012/l, white blood cells 9x109/l, glucose 11 mmol/l, protein 55 g/l, serum amylase: 150 ME/l (normal 40-140 ME/l), serum lipase 50 ME/l (normal 0-50 ME/l). Coprogram: No occult blood, muscle fibers +++, neutral fat +++, starch +++. Identify the pathology developed in the patient?
liver cirrhosis
peptic ulcer
pancreatitis
unspecified ulcerative colitis
chalasia of cardia
A 25-year-old woman consulted a physician with complaints of difficulty swallowing 2-3 seconds after swallowing solid food, which appeared six months ago. Initially she was disturbed by a feeling of filling and squeezing in the chest, and then there appeared difficulty in swallowing food associated with a feeling of overflow of the esophagus, which intensified under emotional stress. Data of objective examination, as well as laboratory investigations including general blood count, sedimentation rate, glucose, creatinine, and liver and blood enzymes levels were within normal limits. What is the pathogenesis of the swallowing disorder in this patient?
deficiency of vasoactive intestinal polypeptide
decreased gastrin production
excess nitric oxide
Hypersecretion of HCl
increased production of secretin
What kind of arrhythmia?
Atrial fibrillation
sinus bradycardia
3rd degree atrioventricular block
1st degree atrioventricular block
2nd degree atrioventricular block
A 42-year-old woman has persistent headaches, general weakness, muscle weakness, creeping sensation, polyuria, nocturia. The relative density of urine is 1006-1008. BP 230/120 mm Hg. Art. In the blood, the sodium content is increased and the potassium content is reduced. Ultrasound examination revealed a tumor of the right adrenal gland. What is the form of arterial hypertension in the patient?
endocrine
renal renoprivative
essential
neurogenic reflex
renal renovascular
A woman, 40 years old, complains of a significant increase in body weight. On examination, the person draws attention to the moon-like face, the deposition of fat mainly on the abdomen, neck, swelling in the legs. The examination revealed: blood pressure 160/100 mm Hg, hyperglycemia, hypokalemia, an increase in blood and urine glucocorticoids, ultrasound revealed an adrenal tumor. What is the form of arterial hypertension in the patient?
endocrine
renal
essential
neurogenic reflex
hemodynamic
A 45-year-old man, who has been observed for 7 years with chronic renal failure, has an increase in blood pressure up to 180/130 mm Hg. What is the form of arterial hypertension in the patient?
endocrine
renal renoprivative
essential
neurogenic reflex
renal renovascular
A 63-year-old man suffering from bronchial asthma has been taking glucocorticoids for several years. During these years, body weight gradually increased, diabetes mellitus and arterial hypertension developed. What is the form of arterial hypertension in the patient?
endocrine
renal
essential
primary
hemodynamic
