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Pathphysio 2 51-65

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

A female patient, age 45 years, had a biochemical blood test: Total protein 45 g/l, albumin 25 g/l, globulin 20 g/l, urea 5.5 mmol/l, creatinine 80 µmol/l, glucose 3.2 mmol/l, total bilirubin 50 µmol/l, Conjugated bilirubin 30 µmol/L, unconjugated bilirubin 20 µmol/L, total cholesterol 3.5 mmol/L, ALT 85 ME/L, AST 70 ME/L. Identify the most likely pathology in which this test might be?

a)

parenchymatous jaundice

b)

Hemolytic jaundice

c)

mechanical jaundice

d)

pancreatitis

e)

dumping syndrome

2.

A 35-year-old man complains of severe epigastric pain occurring 2-3 hours after meals and at night; recently, the pain has become accompanied by nausea and sometimes vomiting. There were two episodes of melena. X-ray examination reveals the 'niche' symptom. Laboratory examination: hemoglobin 90 g/l, erythrocytes 3.5x1012/l, leukocytes 8x109/l. Biopsy of the ulcer site: Helicobacter pylori +++. Gastric secretion analysis revealed increased levels of basal secretion, total acidity, free and bound HCI, and pepsin. Define the pathology most likely to develop in the patient?

a)

cardia achalasia

b)

acute pancreatitis

c)

gastric ulcer

d)

duodenal ulcer

e)

chronic pancreatitis

3.

A 35-year-old man complains of severe epigastric pain occurring 2-3 hours after meals and at night; recently, the pain has become accompanied by nausea and sometimes vomiting. There were two episodes of melena. A radiograph shows the 'niche' symptom. Laboratory examination: hemoglobin 90 g/l, erythrocytes 3.5x1012/l, leukocytes 8x109/l. Biopsy of the ulcer site: Helicobacter pylori +++. Analysis of gastric secretion revealed increased levels of basal secretion, total acidity, free and bound HCI, and pepsin. What is the most likely mechanism of ulcer formation under the influence of Helicobacter pylori?

a)

prolonged spasm of blood vessels and muscles of the stomach and intestines

b)

increased secretion and acidity of gastric juice

c)

stimulation of gastric T-lymphocytes to damage epithelial cells

d)

increased secretion of pepsinogen-1

e)

increase in acid-aggressive activity of gastric juice

4.

A patient with yellow skin staining has elevated levels of unconjugated bilirubin in the blood. What is the most likely cause of this pathology?

a)

Hepatocyte damage by hepatitis A viruses

b)

acute blood loss

c)

Decreased osmotic resistance of erythrocytes

d)

bile duct stones

e)

gallbladder dyskinesia

5.

5-year-old child has increased salivation, spitting, and maceration of the skin around the mouth. Which of the following is the most likely consequence of this pathology?

a)

xerostomia

b)

hypokalemia

c)

multiple dental caries

d)

oral mucosal atrophy

e)

hyperacidity of gastric juice

6.

A 45-year-old man complains of bloating, flatulence, and liquid stools. These symptoms appeared several months ago, occurring 30-60 minutes after breakfast. Every day he eats cereal with milk and yogurt for breakfast. Physical examination revealed no abnormalities. The patient was suggested to stop taking dairy products for 1 week. All his symptoms disappeared. What is the most likely cause of this pathology?

a)

malabsorption syndrome

b)

Galactose intolerance

c)

Intestinal dysbacteriosis

d)

chronic pancreatitis

e)

depleted gastric acidity

7.

A 65-year-old man has been diagnosed with a mechanical type of constipation. The patient most likely has diverticulosis of the colon

a)

endocrine disorder

b)

increased extraintestinal water loss

c)

irritable bowel syndrome

d)

decreased food intake

8.

A 55-year-old woman with chronic hepatic insufficiency showed prolongation of prothrombin time, decreased prothrombin index with normal fibrinogen content and normal thrombin time. What is the leading factor in the pathogenesis of changes in the patient's hemostasis parameters?

a)

deficiency of vitamin K-dependent clotting factors

b)

dysfibrinogenemia

c)

abundance of anticoagulants in the blood

d)

An impairment of the internal prothrombinase activation mechanism

e)

Disorder of external mechanism of prothrombinase activation

9.

A 55-year-old man complains of bloating, emaciation, frequent diarrhea, and vomiting. The man abuses alcohol. Laboratory findings. Blood: hemoglobin 110 g/l, red blood cells 3.4x1012/l, white blood cells 9x109/l, glucose 11 mmol/l, protein 55 g/l, serum amylase: 150 ME/l (normal 40-140 ME/l), serum lipase 50 ME/l (normal 0-50 ME/l). Coprogram: No occult blood, muscle fibers +++, neutral fat +++, starch +++. Identify the pathology developed in the patient?

a)

liver cirrhosis

b)

peptic ulcer

c)

pancreatitis

d)

unspecified ulcerative colitis

e)

chalasia of cardia

10.

A 25-year-old woman consulted a physician with complaints of difficulty swallowing 2-3 seconds after swallowing solid food, which appeared six months ago. Initially she was disturbed by a feeling of filling and squeezing in the chest, and then there appeared difficulty in swallowing food associated with a feeling of overflow of the esophagus, which intensified under emotional stress. Data of objective examination, as well as laboratory investigations including general blood count, sedimentation rate, glucose, creatinine, and liver and blood enzymes levels were within normal limits. What is the pathogenesis of the swallowing disorder in this patient?

a)

deficiency of vasoactive intestinal polypeptide

b)

decreased gastrin production

c)

excess nitric oxide

d)

Hypersecretion of HCl

e)

increased production of secretin

11.

What kind of arrhythmia?

a)

Atrial fibrillation

b)

sinus bradycardia

c)

3rd degree atrioventricular block

d)

1st degree atrioventricular block

e)

2nd degree atrioventricular block

12.

A 42-year-old woman has persistent headaches, general weakness, muscle weakness, creeping sensation, polyuria, nocturia. The relative density of urine is 1006-1008. BP 230/120 mm Hg. Art. In the blood, the sodium content is increased and the potassium content is reduced. Ultrasound examination revealed a tumor of the right adrenal gland. What is the form of arterial hypertension in the patient?

a)

endocrine

b)

renal renoprivative

c)

essential

d)

neurogenic reflex

e)

renal renovascular

13.

A woman, 40 years old, complains of a significant increase in body weight. On examination, the person draws attention to the moon-like face, the deposition of fat mainly on the abdomen, neck, swelling in the legs. The examination revealed: blood pressure 160/100 mm Hg, hyperglycemia, hypokalemia, an increase in blood and urine glucocorticoids, ultrasound revealed an adrenal tumor. What is the form of arterial hypertension in the patient?

a)

endocrine

b)

renal

c)

essential

d)

neurogenic reflex

e)

hemodynamic

14.

A 45-year-old man, who has been observed for 7 years with chronic renal failure, has an increase in blood pressure up to 180/130 mm Hg. What is the form of arterial hypertension in the patient?

a)

endocrine

b)

renal renoprivative

c)

essential

d)

neurogenic reflex

e)

renal renovascular

15.

A 63-year-old man suffering from bronchial asthma has been taking glucocorticoids for several years. During these years, body weight gradually increased, diabetes mellitus and arterial hypertension developed. What is the form of arterial hypertension in the patient?

a)

endocrine

b)

renal

c)

essential

d)

primary

e)

hemodynamic