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Wound Healing and Fracture Healing Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

Complication of wound healing due to excessive collagen deposition is

a)

Dehiscence

b)

Ulceration

c)

Hypertrophic scar

d)

Keloid

2.

Wound dehiscence is caused mainly by

a)

Excess collagen synthesis

b)

Increased angiogenesis

c)

Inadequate scar formation

d)

Excess epithelialization

3.

Ulceration in wound healing is commonly due to

a)

Poor vascular supply

b)

Excess growth factors

c)

Increased collagen

d)

Hyperplasia

4.

Hypertrophic scars differ from keloids in that hypertrophic scars

a)

Extend beyond wound margins

b)

Regress with time

c)

Have no collagen

d)

Occur only in ear lobes

5.

Most important growth factor for fibroblast migration and proliferation is

a)

EGF

b)

PDGF

c)

VEGF

d)

FGF

6.

Growth factor responsible for angiogenesis in wound healing is

a)

EGF

b)

TGF-β

c)

VEGF

d)

IL-1

7.

TGF-β primarily promotes

a)

Inflammation

b)

Collagen synthesis and fibrosis

c)

Epithelialization only

d)

Neutrophil chemotaxis

8.

EGF mainly stimulates

a)

Collagen degradation

b)

Endothelial cell apoptosis

c)

Epithelial cell proliferation

d)

Neutrophil adhesion

9.

FGF is involved mainly in

a)

Angiogenesis and fibroblast proliferation

b)

Complement activation

c)

Platelet aggregation

d)

Apoptosis

10.

Chemotaxis refers to

a)

Random leukocyte movement

b)

Movement along chemical gradient

c)

Passive transport of cells

d)

Cell proliferation

11.

Most potent chemotactic factor for neutrophils is

a)

C3a

b)

IL-1

c)

C5a

d)

Histamine

12.

Bacterial products causing chemotaxis include

a)

Endotoxins

b)

Exotoxins

c)

N-formyl methionyl peptides

d)

Teichoic acid

13.

Leukotriene responsible for chemotaxis is

a)

LTC4

b)

LTD4

c)

LTB4

d)

PGE2

14.

Mechanism of leukocyte movement during chemotaxis involves

a)

Actin polymerization

b)

Microtubule breakdown

c)

Cell swelling

d)

Nuclear fragmentation

15.

Fracture healing by primary union occurs when

a)

There is infection

b)

There is wide gap between fragments

c)

Fragments are closely apposed and immobilized

d)

There is poor blood supply

16.

Secondary fracture healing is characterized by

a)

No callus formation

b)

Abundant callus formation

c)

Absence of inflammation

d)

Direct osteonal healing

17.

Soft callus is composed mainly of

a)

Bone only

b)

Cartilage and fibrous tissue

c)

Mineralized bone

d)

Fatty tissue

18.

Hard callus formation involves

a)

Cartilage deposition only

b)

Endochondral ossification

c)

Intramembranous ossification only

d)

No ossification

19.

Final stage of fracture healing is

a)

Inflammation

b)

Callus formation

c)

Remodeling

d)

Angiogenesis

20.

Non-union of fracture occurs due to

a)

Good blood supply

b)

Early mobilization

c)

Infection and inadequate immobilization

d)

Young age

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