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Blood MCQ Test – Batch A

Total questions: 10

Worksheet time: 10mins

Name
Class
Date
1.

Choose the single best response: A middle-aged woman with diabetes mellitus is receiving antitubercular therapy including isoniazid and rifampicin. During treatment, she develops deep vein thrombosis and is initiated on warfarin. Despite adequate dosing, her prothrombin time (PT/INR remains subtherapeutic). What is the most appropriate next step in management?

a)

Increase the dose of warfarin

b)

Replace warfarin with acenocoumarin

c)

Discontinue rifampicin and substitute with ethambutol

d)

Start low-molecular-weight heparin (LMWH)

2.

Choose the single best response: Heparin therapy should be monitored with intermittent estimation of:

a)

Bleeding time

b)

Prothrombin time

c)

aPTT

d)

All of the above

3.

Choose the single best response: Which of the following metabolic reactions require vitamin B12 but not folate?

a)

Conversion of malonic acid to succinic acid

b)

Conversion of homocysteine to methionine

c)

Conversion of serine to glycine

d)

Thymidylate synthesis

4.

Choose the single best response: A 40-year-old man has megaloblastic anemia and early signs of neurological abnormality. The drug most probably required is:

a)

Folic acid

b)

Iron sulphate

c)

Erythropoietin

d)

Vitamin B12

5.

Choose the single best response: Idarucizumab is the specific antidote for:

a)

Rivaroxaban

b)

Dabigatran

c)

Apixaban

d)

Edoxaban

6.

Choose the single best response: A patient with burns and massive plasma loss is admitted to ICU. Which plasma expander is physiologically most ideal?

a)

Albumin

b)

Dextran

c)

Gelatin polymer

d)

Hydroxyethyl starch

7.

Choose the single best response: The mechanism of action of clopidogrel is:

a)

ADP receptor inhibitor

b)

Thromboxane A2 synthesis inhibitor

c)

Glycoprotein IIb/IIIa inhibitor

d)

Platelet serotonin receptor inhibitor

8.

Choose the single best response: Which of these is an indication of tranexamic acid

a)

Menorrhagia

b)

Cerebrovascular accident

c)

Hematuria

d)

Recurrent abortion

9.

Choose the single best response: Which of these is a contraindication to the use of reteplase?

a)

History of myocardial infarction

b)

Surgery in the past 5 years

c)

Prior intracranial hemorrhage

d)

Prior use of reteplase

10.

Choose the single best response: Tranexaemic acid is a specific antidote of:

a)

Fibrinolytic drugs

b)

Organophosphates

c)

Barbiturates

d)

Heparin