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WorksheetsPharmacology Quiz
Total questions: 10
Worksheet time: 5mins
A patient with heart failure is prescribed Digoxin. Which of the following electrolyte disturbances most significantly increases the risk of Digoxin toxicity?
Hyperkalemia
Hypocalcemia
Hypokalemia
Hypernatremia
Which class of diuretics acts by inhibiting the Na^+/K^+/2Cl^- cotransporter in the thick ascending limb of the loop of Henle and is known to cause ototoxicity?
Thiazide diuretics
Carbonic anhydrase inhibitors
Loop diuretics (e.g., Furosemide)
Potassium-sparing diuretics
"Aliskiren" is a relatively newer antihypertensive agent that acts by which mechanism?
Competitively inhibiting ACE
Directly inhibiting Renin activity
Blocking Angiotensin II receptors
Inhibiting Aldosterone synthase
A patient treated with an ACE inhibitor for hypertension develops a persistent, dry cough. This side effect is primarily attributed to the accumulation of which substance?
Angiotensin I
Bradykinin
Prostaglandin E2
Renin
Which anti-arrhythmic drug is a Class III agent that blocks Potassium channels but also exhibits Class I, II, and IV properties and is known for causing pulmonary fibrosis and blue-grey skin discoloration?
Lidocaine
Verapamil
Amiodarone
Procainamide
The "Cheese Reaction" (hypertensive crisis) in patients taking non-selective MAO inhibitors occurs when they consume foods rich in Tyramine because Tyramine:
Acts as a direct alpha-1 receptor agonist
Inhibits the reuptake of Serotonin
Displaces stored Norepinephrine from synaptic vesicles
Competes with Dopamine for receptor binding
"Levodopa" is administered with "Carbidopa" in the treatment of Parkinson’s disease primarily to:
Increase the transport of Levodopa across the Blood-Brain Barrier
Inhibit the peripheral decarboxylation of Levodopa to Dopamine
Act as a direct agonist at D2 receptors in the striatum
Reduce the breakdown of Dopamine by MAO-B
Which of the following is the specific "Antidote" used to reverse the effects of Benzodiazepine overdose by acting as a competitive antagonist at the GABA-A receptor?
Naloxone
Flumazenil
Disulfiram
N-acetylcysteine
"Phenytoin" follows zero-order kinetics at high therapeutic doses. This means that:
The half-life remains constant regardless of dose
A constant percentage of the drug is eliminated per hour
A constant amount of the drug is eliminated per unit time
The rate of elimination increases linearly with plasma concentration
Which "Typical Antipsychotic" medication is most associated with high potency and a significant risk of Extrapyramidal Side Effects (EPS) such as acute dystonia?
Chlorpromazine
Haloperidol
Clozapine
Quetiapine
