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WorksheetsPathophysiology-Chapter 2 Immunity and Disease- REVIEW
Total questions: 83
Worksheet time: 42mins
The immune system protects the body by distinguishing ____.
inside from outside
positive from negative
self from non-self
upper from lower
Leukocytes that can engulf and destroy pathogens are known as ____.
macrophages
mast cells
neutrophils
phagocytes
Natural killer cells are a type of ____.
albumin
erythrocyte
leukocyte
plasma cell
____ is a group of plasma proteins that assist in the destruction of foreign cells.
Albumin
Complement
ELISA
SLE
Interferons increase the activity of ____.
erythrocytes and leukocytes
macrophages and natural killer cells
phagocytes and neutrophils
plasma and complement
____ can cause dehydration, nausea, disorientation, hallucinations, seizures, and convulsions.
Hypersensitivity
Hyposensitivity
Very high fevers
Very low fevers
After an injury, the damaged cells release potent chemical signals including ____.
albumin and plasma
complement and plasma
histamines and kinins
phagocytes and neutrophils
Adaptive immunity includes two separate but overlapping arms called ____.
antigens and immunoglobulin
B cells and T cells
cell-mediated immunity and humoral immunity
specific immunity and nonspecific immunity
____ provide defense against extracellular antigens like bacterial toxins and bacterial cells.
Antibodies
Erythrocytes
Histamines
Neutrophils
____ provide defense against viruses, abnormal cells, and other intercellular pathogens.
Antibodies
Cell-mediated immunity
Humoral immunity
Immunoglobulins
____ are responsible for cell-mediated immunity.
A cells
B cells
S cells
T cells
Helper T cells become activated by ____ that was engulfed and digested by a phagocyte.
a cytotoxic T cell
an antigen
complement
erythrocytes
The helper T-cell clones stimulate antibody production by ____.
B cells
complement cells
plasma cells
T cells
Ninety percent of lupus patients are ____.
children
older adults
men
women
A common sign of ____ includes a butterfly rash across the cheeks and nose.
ELISA
FACS
IgG
SLE
Cutaneous or discoid lupus affects only the ____, and accounts for approximately 10% of all lupus cases.
brain
heart
lungs
skin
The rash associated with cutaneous lupus is commonly known as a discoid rash because the areas of the rash are ____.
circular
irregular
painful
red
The signs and symptoms of drug-induced lupus erythematosus are similar to those of ____.
ART
EIA
HIV
SLE
If a patient develops ____ lupus, the signs and symptoms will disappear within days to months.
systemic
cutaneous
drug-induced
neonatal
Scleroderma is a chronic autoimmune disease of the ____.
brain
connective tissue
heart
lungs
The most common initial signs and symptoms of ____ are secondary Raynaud's phenomenon, thickening and tightening of the skin of the fingers, and pain in two or more joints.
anaphylaxis
lupus
scleroderma
Sjögren's syndrome
____ is a chronic, progressive autoimmune disease that affects the exocrine glands of the body.
Anaphylaxis
lupus
scleroderma
Sjögren's syndrome
The hallmark symptoms of ____ are dry eyes and mouth.
anaphylaxis
lupus
scleroderma
Sjögren's syndrome
There are several different types of hypersensitivity. Type I is known as ____.
cytotoxic
delayed
immediate
immune-complex
There are several different types of hypersensitivity. Type II is known as ____.
cytotoxic
delayed
immediate
immune-complex
There are several different types of hypersensitivity. Type III is known as _____
cytotoxic
delayed
immediate
immune-complex
There are several different types of hypersensitivity. Type IV is known as _____
cytotoxic
delayed
immediate
immune-complex
The most common type of allergy is _____
Type I
Type II
Type III
Type IV
A Type I allergic reaction is triggered by _____, the immunoglobulin that responds to the presence of allergens.
IgA
IgD
IgE
IgG
An example of _____ hypersensitivity is the response to an incompatible blood transfusion.
cytotoxic
delayed
immediate
immune-complex
The delay in Type IV hypersensitivity occurs because the allergy is due to the action of _____
B cells
histamine
mast cells
T cells
Allergy shots induce the production of _____ in the blood, which coats the allergen and blocks it from binding to IgE in the tissues.
IgA
IgD
IgG
IgM
AIDS is characterized by a reduction in the number of _____
B cells
mast cells
Reed-Sternberg cells
T cells
The _____ stage of an HIV infection is when an HIV-infected patient experiences symptoms but has not yet developed AIDS.
first
second
third
fourth
The human immunodeficiency virus infects and kills _____
antibodies
B cells
cytotoxic T cells
helper T cells
HIV is diagnosed using a(n) _____ to detect HIV antibodies in the blood.
C-reactive protein test
flow cytometry test
agglutination test
ELISA test
At the _____ stage the patient has one of the AIDS indicators diseases and a helper T cell count of less than 200.
first
second
third
fourth
The etiology of Hodgkin's lymphoma is _____
autoimmune
bacterial
idiopathic
viral
Non-Hodgkin's lymphoma is a cancer of the body's _____
autoantibodies
immune system
inflammatory response
lymphocytes
_____ may be treated with chemotherapy, radiation therapy, or a bone marrow transplant.
Hodgkin's lymphoma
Lupus
Scleroderma
Sjögren's syndrome
Nonspecific immunity must be primed by an initial exposure to an antigen before it can protect the body against disease.
True
False
Nonspecific immunity is present at birth and provides immediate, short-term protection against any antigen.
True
False
Secretions such as tears, saliva, sweat, and sebum contain chemicals that destroy foreign invaders.
True
False
While complement is part of nonspecific immunity, it helps both nonspecific and specific immunity.
True
False
Natural killer cells recognize and eliminate virus-infected cells and bacteria-infected cells.
True
False
The inflammatory response can be triggered by infection, trauma, intense heat, and chemicals.
True
False
Specific immunity is also known as adaptive immunity.
True
False
The first exposure to an antigen triggers cell-mediated immunity.
True
False
Memory T cells are responsible for a more potent and rapid antibody response during subsequent exposures to the same antigen.
True
False
Because of reduced antibody production, vaccines are less likely to produce immunity in older people.
True
False
Autoimmunity has no known cause, but it can be easily prevented.
True
False
The etiology of lupus is idiopathic.
True
False
Lupus can be easily diagnosed using a flow cytometry test.
True
False
Scleroderma is four times more common in men than in women.
True
False
Of the two major forms of scleroderma, the more common is systemic sclerosis scleroderma.
True
False
The etiology of scleroderma is idiopathic.
True
False
Sjögren's syndrome can be classified as primary or secondary.
True
False
Scleroderma can be cured with the use of anti-inflammatory drugs, immunosuppressive
True
False
Choose the single best term to correctly complete the statement: ______ is the body's ability to resist infectious disease.
Immunity
Autoimmunity
Inflammation
Allergy
Choose the single best term to correctly complete the statement: An ______ is any foreign substance that, when introduced into the body, activates the immune system.
Antigen
Antibody
Pathogen
Interferon
Choose the single best term to correctly complete the statement: Nonspecific immunity is also known as ______ immunity.
Innate
Adaptive
Humoral
Passive
Choose the single best term to correctly complete the statement: Leukocytes like macrophages and neutrophils can engulf and destroy pathogens, a process called ______.
Phagocytosis
Apoptosis
Opsonization
Hemolysis
Choose the single best term to correctly complete the statement: ______ are antiviral proteins produced by some animal cells after a viral infection.
Interferons
Cytokines
Antibodies
Complement proteins
Choose the single best term to correctly complete the statement: A ______, or an abnormally high body temperature, is a systematic response to an infection.
Fever
Inflammation
Sepsis
Allergy
Choose the single best term to correctly complete the statement: Some of the benefits of ______ include slowing the growth rate of some pathogens, increasing the effect of interferons, enhancing phagocytosis, stimulating antibody production, and accelerating tissue repair.
Fever
Inflammation
Vaccination
Autoimmunity
Choose the single best term to correctly complete the statement: ______ prevents the spread of pathogens, disposes of cell debris and pathogens, and aids in repair of damaged tissue.
Inflammation
Fever
Allergy
Autoimmunity
Choose the single best term to correctly complete the statement: During the inflammatory response, debris and dead and dying cells may accumulate, forming ______.
Pus
Plaque
Scar tissue
Exudate
Choose the single best term to correctly complete the statement: Antibodies are also called ______.
Immunoglobulins
Interferons
Cytotoxins
Antigens
Choose the single best term to correctly complete the statement: A helper ______ cell is also called a CD4 cell.
T
B
NK
Stem
Choose the single best term to correctly complete the statement: ______ T cells are also called CD8 cells.
Cytotoxic
Helper
Memory
Regulatory
Choose the single best term to correctly complete the statement: As humans age, the ______ atrophies, causing a sharp decrease in the number and type of T cells produced.
Thymus
Spleen
Lymph nodes
Bone marrow
Choose the single best term to correctly complete the statement: An Enzyme ______ (EIA) test uses an enzyme to label either the antibody or the antigen.
Immunoassay
Agglutination
Western blot
Electrophoresis
Choose the single best term to correctly complete the statement: C-reactive protein test and erythrocyte sedimentation tests measure general levels of ______ in the body.
Inflammation
Immunity
Allergy
Autoimmunity
Choose the single best term to correctly complete the statement: ______ occurs when individuals develop antibodies called autoantibodies to their own tissues or self antigens.
Autoimmunity
Immunity
Allergy
Innate response
Choose the single best term to correctly complete the statement: ______ is a chronic autoimmune disease that can affect various parts of the body, including the skin, joints, heart, lungs, blood, kidneys, and the brain.
Lupus
Sjögren's syndrome
Hodgkin's disease
Retrovirus infection
Choose the single best term to correctly complete the statement: Seventy percent of people with lupus have the systemic form, called systemic lupus ______ (SLE).
Erythematosus
Neonatal
Autoimmunity
Immunoassay
Choose the single best term to correctly complete the statement: ______ lupus is a rare condition acquired from maternal autoantibodies.
Neonatal
Systemic
Cutaneous
Drug-induced
Choose the single best term to correctly complete the statement: Sjögren's syndrome often affects women during their childbearing years, suggesting a link with Sjögren's syndrome and the hormone ______.
Estrogen
Progesterone
Testosterone
Cortisol
Choose the single best term to correctly complete the statement: An ______, or hypersensitivity, is an extreme immune response to a harmless antigen.
Allergy
Autoimmunity
Immunity
Inflammation
Choose the single best term to correctly complete the statement: Allergy problems arise because the IgE binds to mast cells and induces them to release ______ and other potent chemicals responsible for allergy symptoms.
Histamine
Interferons
Immunoglobulins
Cytotoxins
Choose the single best term to correctly complete the statement: The signs and symptoms of ______ include a sudden drop in blood pressure, narrowing of the airways, rapid and weak pulse, hives, and nausea and vomiting.
Anaphylaxis
Autoimmunity
Inflammation
Fever
Choose the single best term to correctly complete the statement: The cause of AIDS is HIV, a ______ that carries its genetic information as RNA rather than DNA.
Retrovirus
Prion
Bacteriophage
DNA virus
Choose the single best term to correctly complete the statement: Hodgkin's ______, also known as Hodgkin's disease, is a cancer of the immune system.
Lymphoma
Leukemia
Sarcoma
Carcinoma
