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Pathophysiology-Chapter 2 Immunity and Disease- REVIEW

Total questions: 83

Worksheet time: 42mins

Name
Class
Date
1.

The immune system protects the body by distinguishing ____.

a)

inside from outside

b)

positive from negative

c)

self from non-self

d)

upper from lower

2.

Leukocytes that can engulf and destroy pathogens are known as ____.

a)

macrophages

b)

mast cells

c)

neutrophils

d)

phagocytes

3.

Natural killer cells are a type of ____.

a)

albumin

b)

erythrocyte

c)

leukocyte

d)

plasma cell

4.

____ is a group of plasma proteins that assist in the destruction of foreign cells.

a)

Albumin

b)

Complement

c)

ELISA

d)

SLE

5.

Interferons increase the activity of ____.

a)

erythrocytes and leukocytes

b)

macrophages and natural killer cells

c)

phagocytes and neutrophils

d)

plasma and complement

6.

____ can cause dehydration, nausea, disorientation, hallucinations, seizures, and convulsions.

a)

Hypersensitivity

b)

Hyposensitivity

c)

Very high fevers

d)

Very low fevers

7.

After an injury, the damaged cells release potent chemical signals including ____.

a)

albumin and plasma

b)

complement and plasma

c)

histamines and kinins

d)

phagocytes and neutrophils

8.

Adaptive immunity includes two separate but overlapping arms called ____.

a)

antigens and immunoglobulin

b)

B cells and T cells

c)

cell-mediated immunity and humoral immunity

d)

specific immunity and nonspecific immunity

9.

____ provide defense against extracellular antigens like bacterial toxins and bacterial cells.

a)

Antibodies

b)

Erythrocytes

c)

Histamines

d)

Neutrophils

10.

____ provide defense against viruses, abnormal cells, and other intercellular pathogens.

a)

Antibodies

b)

Cell-mediated immunity

c)

Humoral immunity

d)

Immunoglobulins

11.

____ are responsible for cell-mediated immunity.

a)

A cells

b)

B cells

c)

S cells

d)

T cells

12.

Helper T cells become activated by ____ that was engulfed and digested by a phagocyte.

a)

a cytotoxic T cell

b)

an antigen

c)

complement

d)

erythrocytes

13.

The helper T-cell clones stimulate antibody production by ____.

a)

B cells

b)

complement cells

c)

plasma cells

d)

T cells

14.

Ninety percent of lupus patients are ____.

a)

children

b)

older adults

c)

men

d)

women

15.

A common sign of ____ includes a butterfly rash across the cheeks and nose.

a)

ELISA

b)

FACS

c)

IgG

d)

SLE

16.

Cutaneous or discoid lupus affects only the ____, and accounts for approximately 10% of all lupus cases.

a)

brain

b)

heart

c)

lungs

d)

skin

17.

The rash associated with cutaneous lupus is commonly known as a discoid rash because the areas of the rash are ____.

a)

circular

b)

irregular

c)

painful

d)

red

18.

The signs and symptoms of drug-induced lupus erythematosus are similar to those of ____.

a)

ART

b)

EIA

c)

HIV

d)

SLE

19.

If a patient develops ____ lupus, the signs and symptoms will disappear within days to months.

a)

systemic

b)

cutaneous

c)

drug-induced

d)

neonatal

20.

Scleroderma is a chronic autoimmune disease of the ____.

a)

brain

b)

connective tissue

c)

heart

d)

lungs

21.

The most common initial signs and symptoms of ____ are secondary Raynaud's phenomenon, thickening and tightening of the skin of the fingers, and pain in two or more joints.

a)

anaphylaxis

b)

lupus

c)

scleroderma

d)

Sjögren's syndrome

22.

____ is a chronic, progressive autoimmune disease that affects the exocrine glands of the body.

a)

Anaphylaxis

b)

lupus

c)

scleroderma

d)

Sjögren's syndrome

23.

The hallmark symptoms of ____ are dry eyes and mouth.

a)

anaphylaxis

b)

lupus

c)

scleroderma

d)

Sjögren's syndrome

24.

There are several different types of hypersensitivity. Type I is known as ____.

a)

cytotoxic

b)

delayed

c)

immediate

d)

immune-complex

25.

There are several different types of hypersensitivity. Type II is known as ____.

a)

cytotoxic

b)

delayed

c)

immediate

d)

immune-complex

26.

There are several different types of hypersensitivity. Type III is known as _____

a)

cytotoxic

b)

delayed

c)

immediate

d)

immune-complex

27.

There are several different types of hypersensitivity. Type IV is known as _____

a)

cytotoxic

b)

delayed

c)

immediate

d)

immune-complex

28.

The most common type of allergy is _____

a)

Type I

b)

Type II

c)

Type III

d)

Type IV

29.

A Type I allergic reaction is triggered by _____, the immunoglobulin that responds to the presence of allergens.

a)

IgA

b)

IgD

c)

IgE

d)

IgG

30.

An example of _____ hypersensitivity is the response to an incompatible blood transfusion.

a)

cytotoxic

b)

delayed

c)

immediate

d)

immune-complex

31.

The delay in Type IV hypersensitivity occurs because the allergy is due to the action of _____

a)

B cells

b)

histamine

c)

mast cells

d)

T cells

32.

Allergy shots induce the production of _____ in the blood, which coats the allergen and blocks it from binding to IgE in the tissues.

a)

IgA

b)

IgD

c)

IgG

d)

IgM

33.

AIDS is characterized by a reduction in the number of _____

a)

B cells

b)

mast cells

c)

Reed-Sternberg cells

d)

T cells

34.

The _____ stage of an HIV infection is when an HIV-infected patient experiences symptoms but has not yet developed AIDS.

a)

first

b)

second

c)

third

d)

fourth

35.

The human immunodeficiency virus infects and kills _____

a)

antibodies

b)

B cells

c)

cytotoxic T cells

d)

helper T cells

36.

HIV is diagnosed using a(n) _____ to detect HIV antibodies in the blood.

a)

C-reactive protein test

b)

flow cytometry test

c)

agglutination test

d)

ELISA test

37.

At the _____ stage the patient has one of the AIDS indicators diseases and a helper T cell count of less than 200.

a)

first

b)

second

c)

third

d)

fourth

38.

The etiology of Hodgkin's lymphoma is _____

a)

autoimmune

b)

bacterial

c)

idiopathic

d)

viral

39.

Non-Hodgkin's lymphoma is a cancer of the body's _____

a)

autoantibodies

b)

immune system

c)

inflammatory response

d)

lymphocytes

40.

_____ may be treated with chemotherapy, radiation therapy, or a bone marrow transplant.

a)

Hodgkin's lymphoma

b)

Lupus

c)

Scleroderma

d)

Sjögren's syndrome

41.

Nonspecific immunity must be primed by an initial exposure to an antigen before it can protect the body against disease.

a)

True

b)

False

42.

Nonspecific immunity is present at birth and provides immediate, short-term protection against any antigen.

a)

True

b)

False

43.

Secretions such as tears, saliva, sweat, and sebum contain chemicals that destroy foreign invaders.

a)

True

b)

False

44.

While complement is part of nonspecific immunity, it helps both nonspecific and specific immunity.

a)

True

b)

False

45.

Natural killer cells recognize and eliminate virus-infected cells and bacteria-infected cells.

a)

True

b)

False

46.

The inflammatory response can be triggered by infection, trauma, intense heat, and chemicals.

a)

True

b)

False

47.

Specific immunity is also known as adaptive immunity.

a)

True

b)

False

48.

The first exposure to an antigen triggers cell-mediated immunity.

a)

True

b)

False

49.

Memory T cells are responsible for a more potent and rapid antibody response during subsequent exposures to the same antigen.

a)

True

b)

False

50.

Because of reduced antibody production, vaccines are less likely to produce immunity in older people.

a)

True

b)

False

51.

Autoimmunity has no known cause, but it can be easily prevented.

a)

True

b)

False

52.

The etiology of lupus is idiopathic.

a)

True

b)

False

53.

Lupus can be easily diagnosed using a flow cytometry test.

a)

True

b)

False

54.

Scleroderma is four times more common in men than in women.

a)

True

b)

False

55.

Of the two major forms of scleroderma, the more common is systemic sclerosis scleroderma.

a)

True

b)

False

56.

The etiology of scleroderma is idiopathic.

a)

True

b)

False

57.

Sjögren's syndrome can be classified as primary or secondary.

a)

True

b)

False

58.

Scleroderma can be cured with the use of anti-inflammatory drugs, immunosuppressive

a)

True

b)

False

59.

Choose the single best term to correctly complete the statement: ______ is the body's ability to resist infectious disease.

a)

Immunity

b)

Autoimmunity

c)

Inflammation

d)

Allergy

60.

Choose the single best term to correctly complete the statement: An ______ is any foreign substance that, when introduced into the body, activates the immune system.

a)

Antigen

b)

Antibody

c)

Pathogen

d)

Interferon

61.

Choose the single best term to correctly complete the statement: Nonspecific immunity is also known as ______ immunity.

a)

Innate

b)

Adaptive

c)

Humoral

d)

Passive

62.

Choose the single best term to correctly complete the statement: Leukocytes like macrophages and neutrophils can engulf and destroy pathogens, a process called ______.

a)

Phagocytosis

b)

Apoptosis

c)

Opsonization

d)

Hemolysis

63.

Choose the single best term to correctly complete the statement: ______ are antiviral proteins produced by some animal cells after a viral infection.

a)

Interferons

b)

Cytokines

c)

Antibodies

d)

Complement proteins

64.

Choose the single best term to correctly complete the statement: A ______, or an abnormally high body temperature, is a systematic response to an infection.

a)

Fever

b)

Inflammation

c)

Sepsis

d)

Allergy

65.

Choose the single best term to correctly complete the statement: Some of the benefits of ______ include slowing the growth rate of some pathogens, increasing the effect of interferons, enhancing phagocytosis, stimulating antibody production, and accelerating tissue repair.

a)

Fever

b)

Inflammation

c)

Vaccination

d)

Autoimmunity

66.

Choose the single best term to correctly complete the statement: ______ prevents the spread of pathogens, disposes of cell debris and pathogens, and aids in repair of damaged tissue.

a)

Inflammation

b)

Fever

c)

Allergy

d)

Autoimmunity

67.

Choose the single best term to correctly complete the statement: During the inflammatory response, debris and dead and dying cells may accumulate, forming ______.

a)

Pus

b)

Plaque

c)

Scar tissue

d)

Exudate

68.

Choose the single best term to correctly complete the statement: Antibodies are also called ______.

a)

Immunoglobulins

b)

Interferons

c)

Cytotoxins

d)

Antigens

69.

Choose the single best term to correctly complete the statement: A helper ______ cell is also called a CD4 cell.

a)

T

b)

B

c)

NK

d)

Stem

70.

Choose the single best term to correctly complete the statement: ______ T cells are also called CD8 cells.

a)

Cytotoxic

b)

Helper

c)

Memory

d)

Regulatory

71.

Choose the single best term to correctly complete the statement: As humans age, the ______ atrophies, causing a sharp decrease in the number and type of T cells produced.

a)

Thymus

b)

Spleen

c)

Lymph nodes

d)

Bone marrow

72.

Choose the single best term to correctly complete the statement: An Enzyme ______ (EIA) test uses an enzyme to label either the antibody or the antigen.

a)

Immunoassay

b)

Agglutination

c)

Western blot

d)

Electrophoresis

73.

Choose the single best term to correctly complete the statement: C-reactive protein test and erythrocyte sedimentation tests measure general levels of ______ in the body.

a)

Inflammation

b)

Immunity

c)

Allergy

d)

Autoimmunity

74.

Choose the single best term to correctly complete the statement: ______ occurs when individuals develop antibodies called autoantibodies to their own tissues or self antigens.

a)

Autoimmunity

b)

Immunity

c)

Allergy

d)

Innate response

75.

Choose the single best term to correctly complete the statement: ______ is a chronic autoimmune disease that can affect various parts of the body, including the skin, joints, heart, lungs, blood, kidneys, and the brain.

a)

Lupus

b)

Sjögren's syndrome

c)

Hodgkin's disease

d)

Retrovirus infection

76.

Choose the single best term to correctly complete the statement: Seventy percent of people with lupus have the systemic form, called systemic lupus ______ (SLE).

a)

Erythematosus

b)

Neonatal

c)

Autoimmunity

d)

Immunoassay

77.

Choose the single best term to correctly complete the statement: ______ lupus is a rare condition acquired from maternal autoantibodies.

a)

Neonatal

b)

Systemic

c)

Cutaneous

d)

Drug-induced

78.

Choose the single best term to correctly complete the statement: Sjögren's syndrome often affects women during their childbearing years, suggesting a link with Sjögren's syndrome and the hormone ______.

a)

Estrogen

b)

Progesterone

c)

Testosterone

d)

Cortisol

79.

Choose the single best term to correctly complete the statement: An ______, or hypersensitivity, is an extreme immune response to a harmless antigen.

a)

Allergy

b)

Autoimmunity

c)

Immunity

d)

Inflammation

80.

Choose the single best term to correctly complete the statement: Allergy problems arise because the IgE binds to mast cells and induces them to release ______ and other potent chemicals responsible for allergy symptoms.

a)

Histamine

b)

Interferons

c)

Immunoglobulins

d)

Cytotoxins

81.

Choose the single best term to correctly complete the statement: The signs and symptoms of ______ include a sudden drop in blood pressure, narrowing of the airways, rapid and weak pulse, hives, and nausea and vomiting.

a)

Anaphylaxis

b)

Autoimmunity

c)

Inflammation

d)

Fever

82.

Choose the single best term to correctly complete the statement: The cause of AIDS is HIV, a ______ that carries its genetic information as RNA rather than DNA.

a)

Retrovirus

b)

Prion

c)

Bacteriophage

d)

DNA virus

83.

Choose the single best term to correctly complete the statement: Hodgkin's ______, also known as Hodgkin's disease, is a cancer of the immune system.

a)

Lymphoma

b)

Leukemia

c)

Sarcoma

d)

Carcinoma