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WorksheetsNCLEX-Style Practice Questions: Disorders of the Immune Response
Total questions: 10
Worksheet time: 5mins
A patient develops wheezing, hypotension, and hives immediately after receiving IV penicillin. Which immune mechanism is responsible for these manifestations?
IgG-mediated complement activation
Immune complex deposition
IgE-mediated mast cell degranulation
T-cell mediated cytotoxicity
A client experiences fever, chills, and hemoglobinuria during a blood transfusion. Which pathophysiologic process is occurring?
Delayed T-cell activation
Antibody-mediated red blood cell destruction
Immune complex inflammation
Autoimmune neutrophil suppression
A child diagnosed with severe combined immunodeficiency (SCID) is highly susceptible to infections. Which immune components are primarily affected?
Complement proteins only
Phagocytic cells only
Both B lymphocytes and T lymphocytes
Natural killer cells only
A patient develops a pruritic vesicular rash 48 hours after contact with poison ivy. Which immune response is responsible?
IgE-mediated histamine release
IgG antibody binding to cell surfaces
Immune complex deposition
T-cell mediated delayed hypersensitivity
Chronic granulomatous disease results in recurrent fungal and bacterial infections due to failure of which immune process?
Antibody production
Complement activation
Respiratory burst in phagocytes
T-helper cell signaling
HIV leads to progressive immune failure primarily through destruction of which cell type?
B lymphocytes
Neutrophils
CD4 T-helper lymphocytes
Natural killer cells
Which finding is most consistent with Type III hypersensitivity?
Immediate airway swelling
Antibody-mediated hemolysis
Immune complex deposition causing vasculitis
Delayed contact dermatitis
A nurse is teaching about anaphylaxis. Which physiologic effect of histamine contributes most to hypotension?
Bronchoconstriction
Increased capillary permeability
Enhanced antibody production
Reduced cardiac contractility
Which statement best explains why patients with SCID develop opportunistic infections?
A. They cannot produce red blood cells.
B. They lack effective antibody and T-cell responses.
Which immune mechanism is most directly responsible for the delayed onset of Type IV hypersensitivity reactions?
A. Antibody synthesis
B. Complement activation
C. T-cell cytokine release
D. Mast cell degranulation
