DNA Replication

Front

What is the role of RNA Primase in DNA replication?

Back

RNA Primase lays down RNA primers for new nucleotide bases.

Front

What are Okazaki fragments and where are they found?

Back

Okazaki fragments are short sequences of DNA nucleotides synthesized on the lagging strand during DNA replication.

Front

Given the DNA strand 5'ATGCTCAGCTGA3', what is the corresponding DNA strand?

Back

3'TACGAGTCGACT5'.

Front

In which direction does DNA replication occur in terms of nucleotide addition?

Back

DNA replication puts down nucleotides from 5' to 3'.

Front

What does it mean for DNA strands to be antiparallel?

Back

Antiparallel means that the two strands of DNA run in opposite directions, with one strand oriented 5' to 3' and the other 3' to 5'.

Front

What is the primary function of DNA polymerase?

Back

DNA polymerase builds new strands by bringing in new nucleotide bases.

Front

What is the significance of the leading and lagging strands in DNA replication?

Back

The leading strand is synthesized continuously, while the lagging strand is synthesized in short segments called Okazaki fragments.

Front

What is the function of helicase in DNA replication?

Back

Helicase unwinds the DNA double helix, separating the two strands to allow replication.

Front

What are the main differences between DNA and RNA?

Back

DNA is double-stranded, contains deoxyribose sugar, and uses thymine; RNA is single-stranded, contains ribose sugar, and uses uracil.

Front

What is the role of ligase in DNA replication?

Back

Ligase joins Okazaki fragments on the lagging strand, sealing the gaps between them.