Chargaff's Rule

Front

What is Chargaff's Rule?

Back

Chargaff's Rule states that in a double-stranded DNA molecule, the amount of adenine (A) is equal to the amount of thymine (T), and the amount of cytosine (C) is equal to the amount of guanine (G).

Front

If a DNA molecule has 29% guanine, what is the percentage of thymine?

Back

21%.

Front

What is the ratio of adenine to thymine in DNA?

Back

1:1.

Front

If a DNA molecule contains 13% thymine, what is the percentage of cytosine?

Back

37%.

Front

In a DNA molecule, if thymine is 32%, what is the percentage of cytosine?

Back

18%.

Front

What does it mean when we say that adenine and thymine are complementary bases?

Back

It means that adenine pairs with thymine in DNA, following Chargaff's Rule.

Front

What is the significance of Chargaff's findings in molecular biology?

Back

Chargaff's findings helped establish the base-pairing rules that are fundamental to the structure of DNA.

Front

How do you calculate the percentage of a nucleotide if you know the percentage of its complementary base?

Back

You subtract the percentage of the known base from 100% and then divide by 2 for the other two bases.

Front

What is the relationship between cytosine and guanine in DNA?

Back

Cytosine pairs with guanine, and their percentages are equal in a double-stranded DNA molecule.

Front

If a DNA sample has 40% adenine, what is the percentage of thymine?

Back

40%.