Biological Effects of Radioactive Radiation

Front

What is the biological effect of radioactive radiation?

Back

Based on excitation and ionization of atoms and/or molecules of living systems.

Front

What are the particles producing a biological effect in radiation biology?

Back

Particles giving their energy partially or totally to the biological object.

Front

What is defined as a 'hit' in radiation biology?

Back

One or more ionizations in the radiosensitive volume of a biological object.

Front

How is the dose-response curve constructed?

Back

The ratio of surviving organisms (N/N0) is plotted on the vertical axis, and the radiation dose is plotted on the horizontal axis.

Front

What is the probability of generating exactly 'n' hits with dose D in volume V?

Back

P(e) = (V/D)^n * e^(-V/D) / n!

Front

How does the number of ionizations depend on radiation dose?

Back

Linearly proportional to the dose.

Front

What is the equation describing the dose-response curve for one hit required for inactivation?

Back

N/N0 = e^(-V/D).

Front

What is D37 in radiation biology?

Back

The dose at which 37% of irradiated objects survive.

Front

What is the principle of indirect action of radiation?

Back

Radiation particles ionize water, producing radicals that damage solute molecules.

Front

What are the products damaging biological objects during irradiation of aqueous solutions?

Back

Hydrated electrons, H•, OH•, H2O2.