Sickle Cell, Malaria and Natural Selection

Front

What shape do the cells of individuals with sickle cell anemia typically have?

Back

C-shaped cells.

Front

What protein in red blood cells carries oxygen throughout the body and is affected in sickle cell disease?

Back

Hemoglobin.

Front

In which type of cells is hemoglobin found?

Back

Red Blood Cells.

Front

How is the malaria parasite transferred to humans?

Back

By mosquitoes.

Front

What happens when sickle-shaped cells stick to vessel walls?

Back

They cause a blockage that slows or stops the flow of blood, preventing oxygen from reaching nearby tissues.

Front

What is sickle cell anemia?

Back

A genetic disorder that causes red blood cells to become misshapen and break down.

Front

What is the relationship between sickle cell trait and malaria?

Back

Individuals with sickle cell trait have some protection against malaria.

Front

What is the primary cause of sickle cell anemia?

Back

A mutation in the HBB gene that codes for hemoglobin.

Front

What are the symptoms of sickle cell disease?

Back

Pain episodes, anemia, swelling, and increased risk of infections.

Front

What is the role of hemoglobin in the body?

Back

To carry oxygen from the lungs to the rest of the body.