Immunology BOC Questions 87-169

Front

What is the enzyme-linked immunosorbent assay (ELISA)?

Back

A laboratory technique used to detect and quantify proteins, such as antibodies or antigens, in a sample using enzyme-linked antibodies.

Front

What is the role of horseradish peroxidase in ELISA?

Back

Horseradish peroxidase is an enzyme used in ELISA to produce a measurable signal, often through a color change, indicating the presence of the target antigen.

Front

What is hyperviscosity syndrome?

Back

A condition characterized by increased blood viscosity, often seen in monoclonal gammopathies, particularly associated with IgM.

Front

Which immunoglobulin class is most commonly associated with hyperviscosity syndrome?

Back

IgM.

Front

What is anaphylaxis?

Back

A severe, potentially life-threatening allergic reaction that occurs rapidly after exposure to an allergen.

Front

What are immediate hypersensitivity reactions?

Back

Reactions that occur within minutes of exposure to an allergen, primarily mediated by IgE antibodies.

Front

What is systemic lupus erythematosus (SLE)?

Back

An autoimmune disease where the immune system attacks its own tissues, leading to inflammation and damage in various organs.

Front

What happens to complement levels during active systemic lupus erythematosus?

Back

Complement levels, particularly C3, are often decreased during active stages of SLE.

Front

What is the classical complement pathway?

Back

A part of the immune system that enhances the ability of antibodies and phagocytic cells to clear pathogens from an organism.

Front

What is the significance of C4 in the classical complement pathway?

Back

C4 is cleaved during the activation of the classical complement pathway, leading to the formation of C3 convertase.