Kuru (infectious disease)

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What is Kuru?

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Kuru is a neurodegenerative disease caused by prion infection, characterized by tremors, loss of coordination, and ultimately death.

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What are prions?

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Prions are misfolded proteins that can induce other proteins to misfold, leading to neurodegenerative diseases.

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How is Kuru transmitted?

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Kuru is transmitted through the consumption of infected human brain tissue, particularly during cannibalistic rituals.

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What are the symptoms of Kuru?

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Symptoms include tremors, loss of coordination, and progressive dementia.

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What is the incubation period for Kuru?

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The incubation period for Kuru can range from several years to decades.

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What is the relationship between Kuru and Creutzfeldt-Jakob Disease (CJD)?

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Both Kuru and CJD are prion diseases, but Kuru is primarily associated with cannibalism, while CJD can occur sporadically or genetically.

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What is a hallmark symptom of Kuru?

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A hallmark symptom of Kuru is the presence of tremors and ataxia.

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What distinguishes familial CJD from sporadic CJD?

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Familial CJD is associated with genetic mutations, while sporadic CJD occurs without a known genetic cause.

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What are transmissible spongiform encephalopathies (TSEs)?

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TSEs are a group of progressive neurodegenerative diseases caused by prions, including Kuru, CJD, and BSE.

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What is the role of T-lymphocytes and B-lymphocytes in prion diseases?

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T-lymphocytes and B-lymphocytes are immune cells that may be involved in the response to prion infections.