PPB 320

Front

The mechanism involved in the anti-seizure activity of carbamazepine is…..

Back

Block of sodium ion channels

Front

The mechanism involved in the anti-seizure activity of phenytoin is……

Back

Block of sodium ion channels

Front

Which one of the following statements about phenytoin is accurate? Displaces sulfonamides from plasma proteins, Drug of choice in myoclonic seizures, Half-life is increased if used with phenobarbital, Isoniazid decreases steady state blood levels of phenytoin, Toxicity may occur with only small increments in dose

Back

Toxicity may occur with only small increments in dose

Front

An intravenous bolus dose of thiopental usually leads to loss of consciousness within 10–15 seconds. If no further drugs are administered, the patient will regain consciousness in just a few minutes. The reason for this, that thiopental is………

Back

Redistributed from brain to other body tissues

Front

Respiratory depression following use of this agent may be reversed by administration of flumazenil. Options: Desflurane, Fentanyl, Ketamine, Midazolam

Back

Midazolam

Front

You have a vial containing 4 mL of a 2% solution of lidocaine. How much lidocaine is present in 1 mL?

Back

2 mg

Front

Regarding malignant hyperthermia, it is caused by……..

Back

Dantrolene

Front

Which one of the following is most effective in its management…… (a) Baclofen, (b) Dantrolene, (c) Haloperidol, (d) Halothane, (e) Vecuronium

Back

Dantrolene

Front

A 30-year-old male patient on drug therapy for a psychiatric problem feels “flat”, has gained weight, lost his sex drive, has a slight tremor, and experiences increased thirst and frequent urination. The drug he is most likely taking is:

Back

Lithium

Front

Concerning the proposed mechanisms of action of antidepressant drugs, which one of the following statements is accurate? Escitalopram is a selective inhibitor of 5-HT reuptake, Bupropion is an effective inhibitor of NE and 5-HT transporters, Chronic treatment with an antidepressant often leads to the up-regulation of adrenoceptors, MAO inhibitors used as antidepressants selectively decrease the metabolism of norepinephrine, Elevation in amine metabolites in CSF is characteristic of most depressed patients prior to drug therapy.

Back

Escitalopram is a selective inhibitor of 5-HT reuptake.