Microbiology Multiple Choice Questions

Front

What are 'Clue' cells?

Back

'Clue' cells are vaginal epithelial cells that have a characteristic stippled appearance due to the presence of bacteria, commonly associated with bacterial vaginosis, particularly Gardnerella vaginitis.

Front

What is the mechanism of resistance in Klebsiella pneumoniae that confers resistance to Meropenem?

Back

The mechanism of resistance is primarily due to the production of Carbapenemase, an enzyme that breaks down carbapenem antibiotics.

Front

What is Modified Thayer-Martin media used for?

Back

Modified Thayer-Martin media is a selective culture medium used for the isolation of pathogenic Neisseria species, particularly Neisseria gonorrhoeae.

Front

What organism is most likely identified in a Gram stain showing Gram-negative diplococci in a patient with urethral discharge?

Back

The organism is most likely Neisseria gonorrhoeae, which is known to cause gonorrhea.

Front

What does a penicillin-resistant Neisseria gonorrhoeae produce?

Back

A penicillin-resistant Neisseria gonorrhoeae produces Beta-lactamase, an enzyme that inactivates penicillin.

Front

What is the significance of porin mutations in bacteria?

Back

Porin mutations can lead to reduced permeability of the bacterial cell wall, contributing to antibiotic resistance, particularly in Gram-negative bacteria.

Front

Define Carbapenemase.

Back

Carbapenemase is an enzyme produced by some bacteria that hydrolyzes carbapenem antibiotics, rendering them ineffective.

Front

What is the role of Beta-lactamase in bacterial resistance?

Back

Beta-lactamase is an enzyme that breaks down beta-lactam antibiotics, such as penicillins and cephalosporins, leading to antibiotic resistance.

Front

What type of bacteria are Neisseria species?

Back

Neisseria species are Gram-negative cocci, often found in pairs (diplococci), and are known to cause various infections, including gonorrhea and meningitis.

Front

What is the clinical significance of identifying 'Clue' cells in a patient?

Back

The presence of 'Clue' cells in a vaginal smear is indicative of bacterial vaginosis, which may require treatment to restore normal vaginal flora.