MMSC409 Exam 3 Review

Front

What is the Lewis antigen phenotype for a genotype of Lele and sese?

Back

Le a POS Le b NEG

Front

Which phenotype is associated with resistance to malaria caused by P. vivax in the African American population?

Back

Fya Neg, Fyb Neg

Front

What is the purpose of major cross-matching in blood transfusions?

Back

It is performed prior to transfusion of blood products containing RBCs.

Front

Which antibody in the P blood group is associated with spontaneous abortion?

Back

Anti-PP1Pk

Front

What is the McLeod phenotype in the Kell system associated with?

Back

Missing supporting XK protein, and associated with decreased RBC survival.

Front

Define Lewis antigens.

Back

Lewis antigens are carbohydrate structures found on red blood cells that can influence blood group typing.

Front

What is the significance of the Fya and Fyb antigens?

Back

They are part of the Duffy blood group system and can affect susceptibility to malaria.

Front

What does a positive result in major cross-matching indicate?

Back

It indicates compatibility between donor and recipient blood.

Front

What is the role of Anti-P antibodies?

Back

They can cause hemolytic disease of the newborn and spontaneous abortion.

Front

Explain the Kell blood group system.

Back

The Kell blood group system includes antigens that can cause transfusion reactions and hemolytic disease.