p53 and the Cell Cycle Flashcard

Front

What is the function of p53 in preventing cancer?

Back

p53 regulates the cell cycle, promotes DNA repair, and induces apoptosis to prevent cancer.

Front

What happens when p53 detects DNA damage during the cell cycle?

Back

It activates DNA repair mechanisms or triggers apoptosis.

Front

What happens when p53 is absent or non-functional in the cell cycle?

Back

Uncontrolled cell division and increased risk of cancer.

Front

Which subtopic of p53 is related to cell cycle checkpoints?

Back

Regulation of the Cell Cycle.

Front

How does p53 regulate the cell cycle?

Back

p53 regulates the cell cycle by halting it at the G1 phase and initiating DNA repair or apoptosis.

Front

What is apoptosis?

Back

Apoptosis is the process of programmed cell death that occurs in multicellular organisms.

Front

What role does p53 play in apoptosis?

Back

p53 can induce apoptosis in response to severe DNA damage to prevent the propagation of damaged cells.

Front

What are cell cycle checkpoints?

Back

Cell cycle checkpoints are control mechanisms that ensure the proper progression of the cell cycle.

Front

What is the G1 phase of the cell cycle?

Back

The G1 phase is the first gap phase where the cell grows and prepares for DNA replication.

Front

What is DNA repair?

Back

DNA repair is the process by which a cell identifies and corrects damage to its DNA.