PODA Exam 2 Fall 2025

Front

WOTF is most likely to be employed in the treatment of Buruli Ulcer?

Back

Sitafloxacin (Gracevit)

Answer explanation

Sitafloxacin (Gracevit)

drug class: fluoroquinolone

Front

What is Hansen’s Disease?

Back

Leprosy; causative agent is Mycobacterium leprae

Front

WOTF inhibits folic acid synthase and can be used in the treatment of Hansen’s Disease?

Back

Dapsone (Aczone) - like a sulfonamide, any drug that has a sulfonamide structure, inhibits folic acid synthase.

Front

WOTF is the active ingredient in ATS? (Acne Topical Solution)

Back

Erythromycin

Front

What is the primary indication of Bactroban (Mupirocin)?

Back

Impetigo

Front

WOTF is an inhibitor of DNA Gyrase?

Back

Finafloxacin (Xtoro)

Answer explanation

A- tetracycline- inhibits the delivery of aminoacyl tRNA (anticodons) to the 30s microsomal subunit

B- macrolide- inhibits 50s

C- tetracycline, fluorocycline

D- aminoglycosides- inhibit 30s

E- fluoroquinolone- "used for otitis externa, swimmer's ear"

Front

Which class of enzymes does DNA gyrase belong to?

Back

topoisomerase II

Front

What is the correct INITIAL DOSE (loading dose) of Omadacycline (Nuzyra) for treating acute bacterial SSSI?

Back

450 mg PO daily for 1-2 days

Answer explanation

PO- intial dose; 450 mg x 1-2 days then 300mg po qd

 

IV- initial dose 200mg once a day, then 100mg iv qd

Front

Which cephalosporin is MOST appropriate for treating nosocomial infections caused by CAPES organisms (Citrobacter, Acinetobacter, Providencia, Enterobacter, Serratia)?

Back

Maxipime

Answer explanation

Cefipime- Maxipime

Front

What is the sulfonamide preparation of choice to treat Typhoid fever?

Back

Sulfamethoxazole and trimethoprim (Bactrim)

Answer explanation

Bactrim SPOC also for:

UTI, by enterobacter

malaria

pcp- given in four equal portions

legiomaines

pneu strep

cholera