Hodgkins Lymphoma

Hodgkins Lymphoma

How much do you remember about lymphoma?

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Caused when:

• B Lymphocytes mutate

• Multiply uncontrollably (cancerous)

• Congregate in the lymph nodes

• Swelling of the lymph nodes (symptom)

Risk factors

• Cause isn't known

• Risk factors

  Epstein -barr virus

  Glandular fever

  Genetic inheritance

Diagnosis

• Biopsy (take some body cells and analyse under the microscope)

• Reed Sternberg cell

• Binucleated cells

How likely are you to survive this cancer?

• Survival rate is 85% over 5 years

Multiple Choice

Which of these are risk factors for Hodgkins lymphoma?

• Epstein -barr virus

• Glandular fever

• Genetic inheritance

• All of them

Multiple Choice

How likely are you to survive Hodgkins Lymphoma

• We're not sure

• 5% over 5 years

• 85% over 5 years

• 85% over 10 years

Multiple Choice

How do we diagnose Hodgkins lymphoma?

• Swollen lymph nodes

• Presence of Reed-sternberg cells

• Presence of Red-sternberg cells

• Presence of Reed-iceberg cells

4 levels of diagnosis

• (4 stages)

Stage 1 or 2

• One or two lymph nodes

• Easier to treat

• Chemotherapy

  followed up with radiotherapy.

Stage 3 or 4

• 3: Both sides of the body or within an organ

• 4: Multiple organs

• Larger and longer doses of chemotherapy + steroids

  Followed by radiotherapy

Open Ended

What do we think Chemotherapy and Radiotherapy are? How do they work?

Lymphocyte predominant

Lymphoma

• Rituximab + chemotherapy

  Monoclonal antibody treatment

• Attaches to the surface of cancerous cells

  Marks them to the immune system

• The immune system of the patient then destroys the cancerous cells

Multiple Choice

Where does Lymphoma form?

• Lymphatic system

• circulatory system

• Lymphocytes

• blood stream

Multiple Choice

Chemotherapy and Radiotherapy can be used to treat Hodgkin's Lymphoma

• True

• False

Multiple Choice

Hodgins Lymphoma has how many stages?

• 1

• 2

• 3

• 4

Multiple Choice

Which of these would be the correct treatment for Stage 4 Hodgkins lymphoma?

• Radiotherapy

• Chemotherapy

• Radiotherapy and Chemotherapy

• Radiotherapy, Chemotherapy & steroids

Multiple Choice

Which of these would be the correct treatment for Lymphocyte predominant Hodgkins lymphoma?

• Rituximab + chemotherapy

• Chemotherapy

• Radiotherapy and Chemotherapy

• Radiotherapy, Chemotherapy & steroids

All of the treatments for lymphoma have side effects

Open Ended

How many side effects for Chemotherapy and radiotherapy can you think of?

Chemotherapy

• Hair loss

• Fatigue

• Appetite loss

• Nausea (sickness)/ Vomiting

• Bowel conditions

• Anaemia

• Low immune system- Risk of infection and Sepsis

Radiotherapy

• Hair loss

• Fatigue

• Sickness

• Diarrhoea

• Infertility

Steroids

• Increased appetite

• Potential weight gain

Multiple Select

Hair loss is a side effect of:

• Chemotherapy

• Radiotherapy

• Steroids

Multiple Select

Bowel problems are a side effect of:

• Chemotherapy

• Radiotherapy

• Steroids

Multiple Choice

Infertility can be a side effect of:

• Chemotherapy

• Radiotherapy

• Steroids

Multiple Choice

Weight gain can be a side effect of:

• Chemotherapy

• Radiotherapy

• Steroids

Open Ended

All of these treatments require going into hospital. Can you think of any side effects that can arise from going into hospital?

Hospital treatment

• Hospital acquired infection

   

• Isolated- depression, anxiety

Open Ended

Any questions?