A/P Ovarian Cancer Case Study

Poll

CQ1: Do you know someone personally that has had cancer?

• Yes

• No

Multiple Choice

CQ2: Abby wondered: what is the difference between cancer and tumor? What do you think?

• The two terms can be used interchangeably as they are synonymous.

• Cancer is a disease that eventually disrupts body functions whereas a tumor is a mass of cells with no apparent function in the body.

• Cancer is a disease which affects men whereas a tumor may affect both men and women.

• Cancer is a disease of the digestive tract whereas a tumor may develop anywhere in the body.

Multiple Choice

CQ3: Normal CA-125 levels are indicated by values of 35 U/ml or less. Abby’s CA-125 levels taken at two different times are indicated below. Is Abby likely to have a cyst or cancer?

• Cyst

• Cancer

Multiple Choice

CQ4: Why does cancer primarily affect older people rather than young people?

• Because the immune system of older people is not as effective in distinguishing normal cells from cancer cells.

• Because older people have been exposed to more carcinogens.

• Because cancer develops after multiple mutations have occurred which takes years to happen.

• None of the above.

Multiple Choice

CQ5: What would you expect cells to be like if they did not have properly functioning p53?

• The absence of p53 inside cells would cause them to divide more rapidly.

• The absence of p53 could cause cells to replicate with damaged DNA that could ultimately lead to cancer.

• The absence of p53 could cause cells to skip mitosis (M phase) and stay in S phase of the cell cycle.

• The absence of p53 would have no effect on the cells.

​Tumor suppressors and oncogenes

​* Mutations in oncogenes and tumor suppressor genes can lead to cancer.

​

​*http://science.education.nih.gov/supplements/nih1/cancer/activities/activity2_animations.htm

​

​- (Animation #5)

Multiple Choice

CQ6: The BRCA1 and BRAC2 genes that may be mutated in Abby’s cells would be considered?

• An oncogene

• A tumor suppressor gene

Multiple Choice

CQ7: How do cancer cells travel through the human body?

• Cancer travels through the body by way of sexual intercourse between a healthy person and one affected by the disease.

• The circulatory system only is responsible for relocating cancer cells.

• The lymphatic system collects fluids from capillaries and with it cancer cells, which are then delivered by the circulatory system.

• They are moved around on neurons throughout the body.

Multiple Choice

CQ8: Can surgery successfully cure a cancer that has metastasized?

• No, all body cells are dividing uncontrollably

• Yes, it could remove all cells with defective cell-cycle regulation

• No, cancer cells are no longer localized in one spot

• Yes, if the tumor is benign