Chromosomal Disorders during Meiosis

Chromosomal Disorders during Meiosis

by Penny Dunning

Multiple Choice

A doctor may use a _________ to examine the chromosomes in a cell.

• x-ray
• blood test
• karyotype
• hemoglobin

Multiple Choice

How many chromosomes are in a normal human karyotype?

• 2

• 23

• 44

• 46

Multiple Choice

Which are shown in a normal human karyotype?

• autosomes

• sex chromosomes

• homologous chromosomes

• all of these are shown in a karyotype

Multiple Choice

What is the correct chromosomes for a male?

• XX

• XY

• Zz

Multiple Choice

What is the correct chromosomes for a female?

• XX

• XY

• Zz

Multiple Choice

In humans, a male has

• one X chromosome only

• two X chromosomes

• one X chromosome and one Y chromosome

• two Y chromosomes

Multiple Choice

What percentage of human sperm cells carry an X chromosome?

• 0%

• 25%

• 50%

• 100%

Multiple Choice

Which of the following combinations of sex chromosomes represents a female?

• XX

• XXXY

• XY

• XXY

Multiple Choice

Human females produce egg cells that have

• one X chromosome

• two X chromosomes

• One X or one Y chromosomes

• one X and one Y chromosome

Multiple Choice

A pair of identical chromosomes shown in a karyotype, one inherited from mom, and one inherited from dad are called

• sister chromotids
• centromeres
• homologous chromosomes
• autosomes

Multiple Choice

Is this Karyotype human?

• Yes
• No
• Impossible to Determine

Multiple Choice

What is the gender of the individual whose karyotype is seen in the image?

• Male
• Female

Multiple Choice

Based on the karyotype, what is the sex of this baby?

• Male

• Female

Multiple Choice

What is the sex of this individual?

• female
• male

Multiple Choice

What is the sex of this individual?

• female
• male

Multiple Choice

Determine the sex of the individual whose karyotype is displayed in the image.

• female
• male

Multiple Choice

Determine the sex of the individual whose karyotype is displayed in the image.

• female
• male

Multiple Choice

Which of the following statements is FALSE?

• Trisomy 16 is the most common chromosomal abnormality, but the fetuses NEVE survive past the first trimester.

• Chromosomal abnormalities usually result from an error that occurred when an egg or sperm cell was developing

• 75% of the first trimester miscarriages are caused by chromosomal abnormalities

• Individuals with Down Syndrome have only one copy of chromosome 21

Multiple Choice

Which of the following statements about chromosomal disorders is INCORRECT?

• Trisomy means that an individual has two copies of a specific chromosome.

• In most cases an embryo with the wrong number of chromosomes does not survive

• A baby can be born with too many or too few chromosomes

• Errors in the number of chromosomes can cause a wide variety of birth defects.

Multiple Choice

Trisomy 21 means you have what?

• Three copies of chromosome 21
• Twenty one copies of chromosome 3
• Three omies and 21 means
• Two copies of chromosome 21

Multiple Choice

What do experts say is the most common form of Down Syndrome?

• Trisomy 47
• Trisomy 46
• Trisomy 21
• Trisomy 23

Multiple Choice

Based on the Karyotype shown, at which chromosome pair can we identify a genetic disorder? 

• Chromosome pair 5
• sex chromosomes
• Chromosome pair 21
• There are no chromosomal disorders

Multiple Choice

Which disease or disorder is the result of having an extra chromosome number 21?

• Edward's

• Down Syndrome

• Jacob's

• Turner syndrome

Multiple Choice

What does this karyotype show?

• trisomy 18

• missing a sex chromosome

• Down's syndrome

Multiple Choice

The karyotype shows an individual with Edward's Syndrome. What is the name of the specific disorder?

• monomy

• trisomy 18

• Down's syndrome

• Jacob's syndrome

Multiple Choice

Which of the following is FALSE?

• Living children with Trisomy 13 or trisomy 18 are more common than children living with trisomy 21.

• The risk of having a baby with Down's increases with maternal age.

• Children born with Trisomy 13 or Trisomy 18 have severe defects and usually die before their first birthday.

• Most individuals born with X or Y chromosomal abnormalities live fairly normal lives.

Multiple Choice

Cri du Chat syndrome is due to

• deletion at chromosome 9

• deletion at chromosome 5

• inversion at chromosome 2

• duplication at chromosome 3

Multiple Choice

Cri-du-Chat Syndrome is caused by what kind of mutation?

• deletion of a section of chromosome 5

• an extra X chromosome

• trisomy 16

• trisomy 18

Multiple Choice

Generally speaking, males have an XY chromosome, and females have an XX chromosome. However, not everyone is born this way.

What is it called when someone has an XXY chromosomes?

• down syndrome

• Klinefelter syndrome

• Archaeopteryx

• dinosaurs

Multiple Choice

• This karyotype shows Trisomy 21
• This karyotype has no abnormality
• This karyotype is missing a sex chromosome (monosomy x)
• This karyotype is from a gamete

Multiple Choice

Girls affected with Turners are usually infertile

• true

• false

Multiple Choice

Girls affected with Turners are usually short

• true

• false

Multiple Choice

Girls affected with Turners show normal intelligence

• true

• false

Multiple Choice

Girls born with Turner Syndrome have an extra X chromosome.

• true

• false

Multiple Choice

Men affected with Kleinfelters are more likely to have learning disabilities.

• true

• false

Multiple Choice

Boys born with Klinefelter Syndrome are usually infertile.

• true

• false

Multiple Choice

About 1 in 500 to 1000 boys are born with the chromosomes XXY.

• true

• false

Multiple Choice

Affected females with this may experience short statue, delayed or absent puberty, and be infertile.

• Turner

• Down

• Klinefelter's

• Edward's

• XXX

Multiple Choice

Which of the following statements about Jacob's syndrome is INCORRECT?

• Most affected males have normal sexual development

• Most affected males are of normal intelligence

• About 1 in 1000 males are born XYY

• Most affected males are infertile

Multiple Choice

Which of the following statements about Triple X females is INCORRECT?

• Affected girls are usually infertile.

• About 1 in 1000 females have an extra X chromosome

• Affected girls undergo normal puberty

• Affected girls tend to be tall.

Multiple Choice

Girls affected with Turners go through normal puberty changes

• true

• false

Multiple Choice

As adults, men with Kleinfelter's tend to have lower than normal levels of testosterone

• true

• false

Multiple Choice

Often times men affected with Klinefelter's are infertile

• true

• false

Multiple Choice

Individuals develop as males, but are often infertile. Affected individuals may have lower than normal testosterone levels as an adult.

• Turner

• Down

• Klinefelter's

• Edward's

• XXX

Multiple Choice

Because the X chromosome contains genes that are vital for normal development, no baby has been born

• with only one X chromosome

• with 3 X chromosomes

• without an X chromosome

• with four X chromosomes

Multiple Choice

This karyotype was taken from a  ________.

• normal female
• female with Down's syndrome
• female with Turner's syndrome
• male with Turner's syndrome

Multiple Choice

Notice the abnormal 23rd chromosome. This individual has an extra X chromosome. What is this?

• Turner's

• Klinefelter's

• Jacob's

• Down's

• Edward's

Multiple Choice

This karyotype is taken from a  ________.

• female with Turner's syndrome
• male with Down's syndrome
• female with Down's syndrome
• normal female

Multiple Choice

What is the chromosomal condition of the individual whose karyotype is seen in the image?

• Trisomy 21 (Down's Syndrome)
• Trisomy 13 (Patau Syndrome)
• Trisomy 18 (Edward's Syndrome)
• XXY Sex Chromosomes (Klinefelter's Syndrome)

Multiple Choice

What is the chromosomal condition of the individual whose karyotype is seen in the image?

• Monosomy X (Turner's Syndrome)
• Trisomy 21 (Down's Syndrome)
• Trisomy 13 (Patau Syndrome)
• Trisomy 18 (Edwards's Syndrome)

Multiple Choice

Notice the abnormal 23rd chromosome.  This individual suffers from which chromosomal genetic disorder?

• Klienfelter's Syndrome
• Down Syndrome
• Cris-du-Chat Syndrome
• Andrew's Syndrome

Multiple Choice

This karyotype was taken from a  _________.

• male with Turner's syndrome
• male with Klinefelter's syndrome
• female with Klinefelter's syndrome
• male with Down's syndrome

Multiple Choice

The following karyotype illustrates an example of which syndrome?

• Turner's Syndrome
• Klienfelter's Syndrome
• Edward's Syndrome
• Down Syndrome