28.2) PGD Lecture

28.2) PGD Lecture

By Ryan Trott

​Copy the notes onto you packet.

​Copy the notes onto you packet.

​We will fill this in from the board in class or from the picture to the right.

Find this page in your packet!

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Multiple Choice

Which process creates cells with less chromosomes than the parent?

• Mitosis

• Meiosis

Multiple Choice

Which process creates four cells from the one parent cell?

• Mitosis

• Meiosis

Multiple Choice

Which process creates sperm and eggs?

• Mitosis

• Meiosis

Karyotyping

A cell is removed from the embryo during metaphase.

1) A cell is removed

2) Chemicals are used to make the chromosomes visible.

3) ​Chromosomes are put into pairs

4) Pairs are compared to normal sets of chromosomes.​

Some text here about the topic of discussion

Multiple Choice

1. Members of the human species have ______ chromosomes organized in ______ pairs.

• 46, 23

• 23, 46

• 23, 23

• 46, 46

Multiple Choice

2a. An organism that has pairs of chromosomes is called _______

• Haploid

• Diploid

Multiple Choice

2b. Organisms that have only one chromosome of each type are called ________.

• Haploid

• Diploid

Multiple Choice

3a. Which picture shows an replicated chromosome?

Multiple Choice

3b. Which picture shows an unreplicated chromosome?

Poll

4. What pattern do you notice on page 3, the page labeled "My Own Karyotype"?

• All the chromosomes have the same color.

• The chromosomes have a random mix of colors.

• The chromosomes perfectly match one of the grandparents.

• The chromosomes have colors from all four grandparents.

Open Ended

Is it possible for you to be more related to one grandparent than another? Explain.

Poll

A chart of human chromosome pairs is called a karyotype. What information is revealed in the karyotype above?

• The sex

• The age

• Trisomy

• Gene Dominance

Cystic Fibrosis Introduction

Go to the the website and read.

1) Please go to the website on the next page and learn about cystic fibrosis.​

2) Use the website to complete the comprehension questions on the next few slides.​

Cystic fibrosis causes lung infections and increasing difficulty with breathing.

65 Roses Story | Cystic Fibrosis Foundation

You can open this webpage in a new tab.

Copy link

Open in new tab

Open Ended

How does Cystic Fibrosis affect the lifestyle of a person who has it?

Multiple Choice

What is the likelihood of a child having Cystic Fibrosis if both parents are carriers?

• 0%

• 25%

• 50%

• 100%

Open Ended

How would you feel as a parent if one of your children was born with a disorder that you carried, but that did not affect you?

Open Ended

If you could guarantee that the next child would not have cystic fibrosis, would you choose to have more children?

This method can help parents to identify if a child has a genetic disorder before they fully develop. Please watch the video.

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Click on this link:​

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​https://youtu.be/i2jrR-jWDX0

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Watch until 3 minutes 30 seconds​.

Preimplantation

Genetic Diagnosis​

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Poll

Do you think testing embryos for genetic conditions is a good idea?

• Yes

• No

Open Ended

What choices are available if the embryo has a genetic condition?

It is possible to use these techniques to choose the biological sex (male/female) of the child.

​

It is estimated that there are 101 males for every 100 females in the world in 2021.

Sex-selection

​

Click on this link:​

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​https://youtu.be/i2jrR-jWDX0

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Watch from 3 minutes 30 seconds​ to the end.

Poll

Do you think sex selection is an acceptable reason for selecting an embryo?

• Yes

• No

• Maybe

Open Ended

What kind of guidelines might distinguish between selections for ‘good’ reasons versus ‘bad’ reasons for choosing an embryo?

Open Ended

Who decides what the ‘good’ and ‘bad’ reasons are?

Poll

A chart of human chromosome pairs is called a karyotype. What information is revealed in the karyotype above?

• The sex

• The age

• Trisomy

• Gene Dominance