Cell Cycle, DNA Replication, and Cancer

Cell Cycle, DNA Replication, and Cancer

​The cell cycle is a series of growth, development, and division. It is composed of 3 stages:

• Interphase (G1, S Phase, G2)

• Mitosis (PMAT)

• Cytokinesis​

Interphase is where the cell spends most of it's life.

​It is composed of 3 phases:

• G1- Growth of the cell

• S Phase- DNA Synthesis (to make DNA), DNA replication

• G2- More growth of the cell, prepares for Mitosis. ​

Cell Cycle: Interphase

Multiple Choice

Recall: What are the 3 stages of the cell cycle? (in order)

• Mitosis, Cytokinesis, Interphase

• Interphase, Mitosis, Cytokinesis

• Interphase, Cytokinesis, Mitosis

• Mitosis, Interphase, Cytokinesis

Multiple Choice

What happens in the G1 phase of interphase?

• Growth of the cell

• DNA replication

• More growth and preparation for mitosis

• Division of the nucleus

Multiple Choice

What happens in the G2 phase of interphase?

• Growth of the cell

• DNA replication

• More growth and preparation for mitosis

• Division of the nucleus

Multiple Choice

What happens in the S phase of interphase?

• Growth of the cell

• DNA replication

• More growth and preparation for mitosis

• Division of the nucleus

​

​ Unwind Pair Up Cover Up

Open Ended

Why is it important for the cell to replicate DNA before mitosis?

Mitosis is where cellular division takes place. Specifically, division of the nucleus.

​It is composed of 4 phases

• Prophase- Nucleus disappears, chromosomes condense, centrioles form

• Metaphase- Chromosomes line up in the MIDDLE

• Anaphase- Chromosomes are pulled APART

• Telophase- Cleavage furrow will form, ready for cellular division

Cell Cycle: Mitosis

Multiple Choice

What stage of mitosis is shown in the image?

• Prophase

• Metaphase

• Anaphase

• Telophase

Multiple Choice

What stage of mitosis is shown in the image?

• Prophase

• Metaphase

• Anaphase

• Telophase

Multiple Choice

What stage of mitosis is shown in the image?

• Prophase

• Metaphase

• Anaphase

• Telophase

Multiple Choice

What stage of mitosis is shown in the image?

• Prophase

• Metaphase

• Anaphase

• Telophase

Open Ended

Cytokinesis is the final stage of the cell cycle. What happens in this stage?

Open Ended

After discussing "cellular differentiation", how would you describe what it is? (Hint: what do you see in the image?) (Complete sentences)

Multiple Choice

If the cell is unable to fix the DNA damage it will "burst" or self destroy itself. What is this called?

• Interphase

• Mitosis

• Apoptosis

• Cytokinesis

Open Ended

What are the cell cycle checkpoints used for? And why are they so important?