Cancer and Cell Cycle

​Cancer and Cell Cycle Regulation

Multiple Choice

What is cancer?

• The heart does not receive enough blood.
• Sudden disruption of blood flow to part of the brain.
• Blood filled weak spot.
• Uncontrolled growth and spread of abnormal cells.

Multiple Choice

Cancer is a consequence of the disruption of the cell cycle

• True
• False

Multiple Choice

What is a term for programmed cell death?

• apoptosis
• necrosis
• cell death
• doom

Draw

Draw a cell with 3 chromosomes in metaphase

Multiple Choice

One difference between a cancer cell and a normal cell is that

• cancer cells divide unconrollably

• normal cells divide uncontrollably

• cancer cells cannot make copies of DNA

• normal cells cannot make copies of DNA

Multiple Choice

________________is a critical point where stop and go signals can regulate the cycle

• Metastasis

• Checkpoint

• Malignant

• Benign

Multiple Choice

What happens when cells undergo uncontrolled division?

• Cancer can develop in that part/organ.

• Normal growth of body occurs.

• Your body will grow rapidly.

• Your body size will become bigger and bigger.

Multiple Choice

Mitosis is a type of cell division in which two                         cells are formed.

• Identical

• Similar

• Different

• Smaller

Open Ended

Defective checkpoints can lead to abnormal growth.

A) What does it mean to be defective?

B) What does it mean to have abnormal growth?

Multiple Choice

Chromosomes move to opposite sides of the cell with the help of                              formed by centrioles.

• Spindle fibres.

• Amino acids.

• Proteins.

• Centrosomes.

Multiple Choice

Suppose a cell already in cytokinesis had a mutation in their DNA. What checkpoint had an error?

• m checkpoint

• s checkpoint

• z checkpoint

• g1 checkpoint

Multiple Choice

Study of mitosis is important for-

• Cancer Research.

• Typhoid

• Lung diseases.

• Cell division.

Multiple Choice

what is cancer?

• the application of biomaterials to improve existing tissues

• the result of an improperly regulated cell cycle

• when a growth factor causes a cell to specialize

• when carbon dioxide is exchanged for oxygen

Open Ended

Unregulated cell division leads to tumors.

A) Describe what it means to have unregulated cell division

Multiple Choice

what happens when a proto-oncogene gets stuck on?

• cell will immediately stop dividing

• cell cycle instantly pauses

• cell will not stop going through the cell cycle

• cell will undergo apoptosis

Multiple Choice

what is NOT a way that cancerous cells are different from regular cells?

• they have different shapes

• they have multiple nuclei

• they have less cytoplasm

• they go through the cell cycle at the same pace

Multiple Choice

Which of the following best defines cancerous cells?

• Unregulated cell growth

• Incapable of creating new DNA

• Lack of mitochondria

• Slow cell replication

Multiple Choice

Cells that "leave" the cell cycle and no longer replicate are considered to be in the ____ phase.

• N0

• G0

• M

• Passive

Open Ended

Uncontrolled production of cyclin proteins, which manage checkpoints, leads to cancer.

A) Describe what it means by uncontrolled production.

Multiple Select

what are the three phases of interphase?

• M

• G1

• S

• G2

Multiple Choice

tumor suppressor genes are like ....

• car brakes

• gas pedals

Open Ended

Tumors cells grow from repeating the cell cycle continuously without stopping.

A) Describe what it means for the cell to repeat the cell cycle continuously?