Lesson: Mutations

-Martinez

" Everything in GREEN is review.
Your notes will begin when you see YELLOW. " 

Multiple Choice

What is a mutation?

• Any change to the DNA sequence.

• Any change to the cell membrane.

• Any change to a cell's homeostasis.

• Any change to the amount of ATP.

Multiple Choice

Anything that causes a mutation is called a

• Dimer

• Monomer

• Mutagen

• Mutant

Match

Match the following terms and definitions

• Addition of N bases; mutated sequence is longer than original

• Removal of N bases; mutated sequence is shorter than original

• mutated sequence is same length as original

• Any change to a DNA sequence

• Anything that can cause a mutation

Insertion

Deletion

Substitution

Mutation

Mutagen

• Insertion

• Deletion

• Substitution

• Mutation

• Mutagen

Dropdown

Mutations in ​

Select answer

genes are harmless.

Multiple Choice

Mutations can result in changes to the amino acid sequences of a protein.  These changes to a protein are a direct result of changes to the –

• shape of the DNA double helix

• sugar-phosphate backbone of the DNA

• sequence of nitrogen bases in the DNA

• phospholipid bilayer in the cell membrane

Multiple Choice

Mutations would be unlikely to harm a cell if the change affected –

• the stop codon of DNA polymerase

• the gene for an unexpressed enzyme 

• the sequence of bases in ribosomal RNA

• the production of proteins in the cytoskeleton

Multiple Choice

Insertion or deletion of nitrogen bases can lead to a change in the reading frame. This is known as a

• substitution mutation

• frameshift mutation

Multiple Choice

Substitution mutations do not change the reading frame.

• True

• False

Multiple Choice

Another name for a substitution mutation is

• frameshift mutation

• point mutation

Match

Match the following terms and definitions.

• Insertions or deletions shift the coding frame to the left or right

• substituting one nitrogen base for another

• The mutation results in no change to the amino acid sequence

• An amino acid sequence is stopped, shortening the protein

• The identity of a single amino acid is changed in a protein

Frameshift Mutation

Point Mutation

Silent Mutation

Nonsense Mutation

Missense Mutation

• Frameshift Mutation

• Point Mutation

• Silent Mutation

• Nonsense Mutation

• Missense Mutation

Poll

Which type of mutation do YOU think is the worst to have?

• Frameshift mutation

• Point Mutation