FOB: Chapter 11

Chapter 11.1: DNA & Genes

Section 11.1

DNA: The Molecule of Heredity

Vocab:
-Nucleotide
-Nitrogenous Base
-Double Helix
-DNA Replication

​I CAN...
Determine how the structure of DNA enables it to reproduce itself accurately.

• Proteins and Enzymes are essential for life​!

• Structure of DNA contains complete instructions for manufacturing ALL proteins.

What is DNA?

• DNA is a polymer with repeating subunits called nucleotides.

• Nucleotides:

  • Simple Sugar

  • Phosphate Group

  • Nitrogenous Base

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Nucleotide Structure

• Simple Sugar = Deoxyribose

• Phosphate Group = 1 Phosphorus surrounded by 4 Oxygen atoms

• Nitrogenous Base = A (adenine), T (thymine), C (cytosine), or G (guanine)

• DNA is made of 2 chains of nucleotides held together by nitrogenous bases.

• Just as teeth of a zipper hold the two sides of the zipper together, the nitrogenous bases of the two nucleotides hold the two strands of DNA together with weak HYDROGEN BONDS.

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Multiple Select

What is DNA?

• A type of sugar

• Instructions for proteins

• Genetic Material

• A type of protein

Multiple Choice

DNA is a polymer made up of:

• fatty acids
• nucleotides
• sugars
• amino acids

• Always equal amounts of C & G or equal amounts of A & T

• 2 strands twisted together = double helix

• Sequence forms unique genetic info

• A-T-T-G-A-C is different from

  T-A-T-A-C-G

• 6 letter word spelled two ways; same letters different meaning.

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Importance of Nucleotide Sequence

Labelling

Nucleotides are made up of:

Drag labels to their correct position on the image

Protein

Complex Sugar

Phosphate Group

Pentose (simple) Sugar

Sulfate Group

Hydrogenous Base

Nitrogenous Base

Multiple Choice

There are 4 types of nitrogenous bases, adenine, cytosine, thymine, and guanine. How do the bases pair in order to create a DNA sequence?

• Adenine pairs with thymine, and cytosine pairs with guanine
• Thymine pairs with cytosine, and adenine pairs with guanine
• Adenine pairs with guanine, and cytosine pairs with thymine
• Adenine pairs with cytosine, and thymine pairs with guanine

• A cell divides by either Mitosis or Meiosis, but FIRST it must make a copy of its chromosomes.

• DNA in the chromosomes is copied through DNA replication.

• 2 molecules are formed, each strand has 1 original strand (blue) and one newly synthesized strand (pink)

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Replication of DNA

• An enzyme breaks the hydrogen bonds between bases that hold the two DNA strands together

  • Unzipping

• As DNA unzips, free floating nucleotides attach to their base pair by H⁺ bonds.

  • Another enzyme bonds these nucleotides into a chain

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​How DNA Replicates

• Process continues until entire molecule has been unzipped and replicated.

• Each new strand is a complement of one of the original, or parent, strands.

• Result = 2 DNA molecules, each of which is identical to the original DNA molecule.

  • Genetic info can then be passed on through Mitosis or Meiosis.
    

Multiple Choice

What must happen before Mitosis or Meiosis can take place?

• Replication of DNA
• Breakdown of DNA
• Duplication of RNA
• Mutation of DNA

Multiple Choice

How are the two new complementary strands of DNA formed from the original strand of DNA?

• • free floating nucleotides attach to their base pair by H⁺ bonds

• • free floating amino acids attach to their base pair by N⁺ bonds

• • free floating phosphate groups attach to their base pair by H⁺ bonds

• • free floating sugars attach to their base pair by N⁺ bonds