Lesson 3: DNA Transcription

Lesson 3: DNA Transcription

Essential Idea: Genetic information
in DNA can be accurately copied and
can be translated to make the
proteins needed by the cell.

Learning Goals:

• Compare and contrast DNA and RNA.

• Explain how the cell “reads” the code in DNA.

• Describe how transcription and translation allow cells to produce the proteins that allow life to function.

RNA

What is RNA?

RNA is a single stranded DNA
molecule that has three roles within
the cell:

1. Carry the coded message in DNA to the cell.

2. Carry amino acids that can be
   chained together to build proteins.

3. Build ribosomes, which are the protein factories in the cell.

Comparing RNA and DNA

• DNA and RNA are both nucleic acids.

• RNA is single-stranded, DNA is
  double-stranded.

• The sugar in RNA is ribose.

• RNA contains uracil (U) and not
  thymine (T). U replaces T.

• DNA is only found in the nucleus where RNA can be in or out of the nucleus.

Multiple Select

Which of the following sequences would be from a DNA molecule?

• ATCGC

• TTCGC

• UCGAU

• UUUAAC

Multiple Select

Which of the following sequences would be from a RNA molecule?

• ATCGC

• TTCGC

• UCGAU

• UUUAAC

Transcription

Transcripton is the process of transcribing (copying) the genetic
code in DNA into RNA.

DNA is too large to leave the nucleus so the code is copied or transcribed into RNA because it can go into the cell.

RNA polymerase, an enzyme attaches itself to a region of DNA called the promoter. It is a region right in front of a gene that is getting ready to be
transcribed.

It transcribes DNA into a molecule called messenger RNA (mRNA). mRNA carries the DNA "message" into the cell.

The mRNA then exits the nucleus into the cytoplasm.

Fill in the Blanks

Determine the RNA code that would be produced by the following DNA sequence:

DNA: ATT AAG GCC GAT AGG ATA

Multiple Choice

I am a single strand.

• DNA
• RNA

Multiple Choice

I include the bases Guanine (G), Cytosine (C), Adenine (A), and Thymine (T).

• DNA
• RNA

Multiple Choice

I include the bases Guanine (G), Cytosine (C), Adenine (A), and Uracil (U).

• DNA
• RNA

Multiple Choice

I have the sugar ribose.

• DNA
• RNA

Multiple Choice

I travel outside of the nucleus.

• DNA
• RNA

Multiple Choice

In DNA, adenine (A) pairs with:

• Cytosine (C)

• Thymine (T)

• Guanine (G)

• Uracil (U)

Multiple Choice

In RNA, adenine (A) pairs with:

• Cytosine (C)

• Thymine (T)

• Guanine (G)

• Uracil (U)

Multiple Choice

Which of the following is FALSE about RNA?

• RNA is single stranded.

• RNA comprises of a ribose sugar.

• RNA bases are: thymine, adenine, cytosine, guanine.

• RNA can be found both inside and outside of the nucleus.

Multiple Choice

What would be the mRNA strand to compliment the DNA strand with the following sequence:
TAC GAA

• AUG CUU
• ATG CTT
• GCA TCC
• GCA UCC