Molbio M2_L1-L2

Open Ended

In what ways do you think molecular biology has transformed the diagnosis of diseases in recent years?

Multiple Choice

Why is the diagnosis of disease considered a crucial aspect in the field of medical technology?

• It helps in choosing the right treatment and improving patient outcomes.

• It is only important for research purposes.

• Diagnosis is not necessary if symptoms are obvious.

• It is mainly used for administrative records.

Multiple Choice

What is cancer?

• The heart does not receive enough blood.
• Sudden disruption of blood flow to part of the brain.
• Blood filled weak spot.
• Uncontrolled growth and spread of abnormal cells.

Multiple Choice

Which of the following gene types, when mutated, can contribute to the development of cancer?

• Proto-oncogenes

• Tumor suppressor genes

• Genome maintenance genes

• All of the above

Open Ended

Explain how mutations in proto-oncogenes and tumor suppressor genes can lead to cancer.

Multiple Choice

Substances or radiation that is known to produce or promote cancer are called

• carcinogens

• kinases

• cyclins

• malignancies

Multiple Select

Which of the following statements about benign and malignant tumors is/are correct?

• Benign tumors are invasive and spread to other tissues.

• Malignant tumors can metastasize and are the leading cause of cancer death.

• Benign tumors are removable and non-invasive.

• Malignant tumors are always non-removable.

Multiple Choice

Which of the following is NOT a characteristic of inherited human diseases as described in the slide?

• Caused by mutant alleles

• Always caused by environmental factors

• Can result from new mutations

• Can be studied by sequence comparison

Multiple Choice

What type of mutation involves substituting a DNA base with a different base?

• point mutation

• frameshift mutation

• silent mutation

• chromosomal mutation

Multiple Choice

Which of the following is a major cause of cervical cancer?

• Human Papillomavirus (HPV)

• Hepatitis C Virus (HCV)

• Cytomegalovirus (CMV)

• Chlamydia

Multiple Choice

Which of the following is NOT a learning objective for the lesson on the role of molecular biology in forensic science?

• Differentiate non-infectious and infectious diseases

• Discuss the role of molecular biology in forensic medicine

• Describe the process of photosynthesis

• Apply molecular techniques in DNA fingerprinting & gene mapping

Open Ended

Explain how DNA testing revolutionized criminalistics and its significance in forensic investigations.

Multiple Choice

Which of the following are key differences between forensic and clinical testing?

• Forensic testing focuses on identity, uses diverse samples, and requires a strict legal chain of custody

• Clinical testing is always performed in uncontrolled environments

• Forensic testing is replenishable and does not require a legal chain of custody

• Clinical testing uses only blood samples

Multiple Choice

Which DNA typing system is primarily used for gender identification?

• VNTR (RFLP)

• STR

• Y-Chromosome markers

• Mitochondrial DNA (mtDNA)

Multiple Choice

In which scenario is mitochondrial DNA (mtDNA) analysis most useful?

• When only shed hairs are available as evidence

• When nuclear DNA is intact and abundant

• When only paternal relatives are available

• When there is no need for DNA analysis

Open Ended

Why was mtDNA analysis necessary in the crime scene case study?

Multiple Choice

Which of the following is NOT a role of molecular methods in disease diagnosis as discussed in the lesson?

• Detecting HPV, HIV, HCV, CMV, and bacterial STIs

• Identifying key genes involved in cancer

• Differentiating between viral and bacterial infections only

• Applying concepts in evaluating diagnostic methods used in Medical Technology

Open Ended

How does molecular biology contribute to the diagnosis of diseases?