Probiotics and Human health

​Probiotics & Human Health

By Active CMU

Biochemistry Staffs

​Activity

09:00 – 10:00 น. : ศึกษา clip VDO จำนวน 2 clips สามารถอ่านเพิ่มเติมได้ตามต้องการ

10:00 – 12:00 น. : ทำ team quiz by Kahoot จำนวน 8 ข้อ จากความรู้ที่ศึกษามาใน  
VDO clips และเฉลย

https://www.youtube.com/watch?v=2ObAE52uMDU&list=PPSV

https://www.youtube.com/watch?v=cDrCpN22bjA&list=PPSV

Activity

10:00 – 14:00 น. ทำ team quiz  “quizzes” จำนวน 8 ข้อ จากความรู้ที่ศึกษามาใน   VDO clips และเฉลย

การแข่งขันระหว่างทีม แข่งเวลาและความถูกต้อง

การเก็บคะแนนดูจากแค่ความถูกต้อง

Multiple Choice

1.Which of the following have significantly co-contributed with microbiome to understand health and disease in individual? According to this clip

• Xenobiotics metabolism

• Metabolism

• Epigenetics

• Genome sequence

• Telomere length

Multiple Choice

2. How does diet impact the gut microbiome?

• A) Changes of diet improve all gut flora growth as their energy source

• B) Diet drives changes in the type of gut flora

• C) Lipid-rich diets suppress all gut flora growth

• D) Protein-rich diets increase all bacteria equally

• E) Choline containing diets improve good bacteria growth

Multiple Choice

3. How can fiber affect the gut microbiome?

• A) Increases good bacteria

• B) Feeds bacteria that produce harmful gases

• C) Promotes carcinogenic bacteria

• D) Reduce all bacterial growth

• E) Causes bacteria to produce trimethylamine oxide

Multiple Choice

4. How have modern genetic sequencing techniques transformed our understanding of the colon's function?

• A) They showed that the colon’s primary role is still water absorption and waste retention

• B) They helped reveal that the colon hosts a complex microbiome crucial for overall health

• C) They proved that all bacteria in the gut can be easily cultured in labs for research

• D) They confirmed that bacteria strains are conserved in the gut of human body

• E) They demonstrated that the colon's role in digestion is insignificant compared to other organs

Health-promoting effects of good bacteria include boosting our immune system, improving digestion and absorption. They make vitamins, inhibit the growth of potential pathogens, and keep us from feeling bloated. Should bad bacteria take roost, they can produce carcinogens, putrefy protein in our gut, produce toxins, mess up our bowel function, and cause infections.

Researchers are still in the process of figuring out which bacteria are which.

Based on studying what comes out of twins, those that eat different habitual diets and stools from around the world, it has become evident that diet has a predominant role on the bacteria in our colon, and the diet-driven changes in it occur within days to weeks.

Milk fat on a piece of pizza, for example, may complex with bile and feed a bacteria that produces the rotten egg gas, hydrogen sulfide, and has experimentally been associated with colitis, inflammatory bowel disease.

Fiber, on the other hand, feeds our good bacteria and decreases inflammation in the colon.

Choline, found in eggs, seafood, and poultry, as well as carnitine in red meat, can be turned into trimethylamine oxide and contribute to heart disease and perhaps fatty liver disease.

And excess iron may muck with our good bacteria and contribute to inflammation as well

Multiple Choice

1. What is the role of short-chain fatty acids produced by gut bacteria?

• They cause steatosis (fatty stool)

• They cause type 2 diabetes or cardiovascular disease

• They suppress inflammation

• They suppress iron toxicity in colon

• They promote colon cancer

Multiple Choice

2. Which of the following components is highly found in beans and helps increase good bacteria in the gut?

• Essential amino acids

• Vitamin B6

• Resistant starch

• Complex carbohydrates

• Resistant protein

Multiple Choice

3. Which of the following is correct about dysbiosis in the gut?

• Consumption of too many MACs

• It is caused by an imbalance of bacterial metabolites

• It is caused by short-chain fatty acids

• It results in imbalance of normal flora

• It is activated by fiber

Multiple Choice

4. How can dysbiosis in the gut microbiome lead to an increase risk of cardiovascular disease, type 2 diabetes, and metabolic syndrome?

• It decreases digestion

• It directly affects neurotransmitter production

• It leads to systemic inflammation

• It activates immunity

• It increases production of short chain fatty acids