Cell Regulation and Cancer Lesson

Multiple Choice

Refer to the diagram below. During the cell cycle, normal cells exit the G1 phase and enter the GO phase where they rest. Typically, cells will reenter the cycle at G1 prior to going on to the S phase. However, abnormal cells such as cancer cells may not be allowed to enter the GO phase to rest. As a result, these cells will most likely –

• mutate during G2 phase

• continuously repeat the cycle

• die after DNA replication

• fail to complete mitosis

Hotspot

Select the correct phase of the Cell Cycle: In this phase the cell checks for errors and prepares for cell division.

Open Ended

Discuss the consequences of disruptions in the cell cycle, especially concerning uncontrolled cell division. Provide an example of a disease that can result from such disruptions.

Multiple Choice

Which checkpoint involves ensuring all DNA has been replicated and "no" errors exist?

• G1

• G2

• M

• S

Multiple Choice

What is the importance of apoptosis?

• To eliminate damaged or unnecessary cells
• To create specialized cells

Multiple Choice

The vertebrae forelimb initially develops in the embryo as a solid mass of tissue. As development progresses, the solid mass near the end of the forelimb is remolded into individual digits. Which of the following best explains the role of apoptosis in the remodeling of the forelimb?

• Apoptosis replaces odd cells with new ones that are less likely to develop mutations

• Apoptosis involves the regulated activation of proteins in specific cells of the developing forelimb that leads to the death of those cells

• Apoptosis involves the destruction of extra cells in the developing forelimb, which provides nutrients for the phagocytic cells

• Apoptosis in the developing forelimb triggers the differentiation of cells whose fate was not already determined

Dropdown

The development of ​

Select answer

(uncontrolled growth) can be relate to ​

Select answer

that affect the ​

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that​

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Multiple Choice

Substances or radiation that is known to produce or promote cancer are called

• carcinogens

• kinases

• cyclins

• malignancies

Poll

How confident do you feel about this topic now?

• Very confident
• Somewhat confident
• Not confident

Match

Match the following

• G1 Checkpoint

• G2 Checkpoint

• Mitosis Checkpoint

Checklist summary:

✓ No DNA damage

✓ Sufficient resources

Checklist summary:

✓ DNA without damage

✓ Chromosome set complete

✓ Enough cell components

Checklist summary:

✓ All sister chromatids attached to mitotic spindle

• Checklist summary:

  ✓ No DNA damage

  ✓ Sufficient resources

• Checklist summary:

  ✓ DNA without damage

  ✓ Chromosome set complete

  ✓ Enough cell components

• Checklist summary:

  ✓ All sister chromatids attached to mitotic spindle