Which of the following is an inherited disease that is due to a base substitution mutation in a gene?

• Trisomy 21
• Sickle cell anemia
• AIDS
• Type II Diabetes

Which of the following is the cause of sickle-cell anemia?

• Tryptophan is replaced by leucine
• Leucine is replaced by valine
• Glutamic acid is replaced by valine
• Lysine is replaced by glutamic acid

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2

What is the cause of sickle-cell anemia?

• A change to the base sequence of a hemoglobin gene
• Mosquitos acting as the vector for malaria
• Iron deficiency due to the malaria parasite
• Production of more white blood cells than red blood cells by bone marrow

A human cell has between 20,000-25,000 genes whereas an E. coli cell has approximately 4,000 genes.  Which of the following statements is true?

• The human genome is larger than the E. coli genome
• There are more genes on each human chromosome than on the E. coli chromosome
• The human cell and the E. coli cell produce approximately the same variety of proteins
• The DNA in both organisms is associated with histones (proteins)

Which of the following statements about homologous chromosomes is correct?

• Each gene is at the same locus on both chromosomes
• They are two identical copies of a parent chromosome which are attached to one another at the centromere
• They always produce identical phenotypes
• They are chromosomes that have identical genes and alleles

What happens in crossing over?

• Exchange of genes during metaphase of mitosis
• Random distribution of chromosomes during meiosis
• Exchange of genetic material between homologous chromosomes
• Homologous chromosomes fail to separate during meiosis

A cell in the testis of a male chimpanzee contains 2n=48 chromosomes.  It then undergoes meiosis.  How many molecules of DNA will be present in the nucleus of the sperm cells just after meiosis?

• 96
• 48
• 24
• 12

If the haploid number of a species is 14, how many chromatids will there be in metaphase I in a dividing diploid cell?

• 7
• 14
• 28
• 56

How many autosomes are there in a human sperm?

• 1
• 22
• 23
• 46

If the amount of DNA in a haploid gamete is represented by X, what is the net quantity of DNA in a cell from the same organism at the start of meiosis?

• 0.5x
• x
• 2x
• 4x

Tags

NGSS.HS-LS3-2