AP Bio: Enzymes and Metabolism

Which process requires an input of energy

• endergonic reactions
• exergonic reactions
• Hydrolysis
• cellular respiration

When the temperature or pH causes the enzyme to change so it no longer works, this is called _______.

• Allosteric
• Substrate
• Denature
• Active Site

Which of the following conclusions can be drawn from this graph?

• The optimum pH of the enzyme is 6.6.
  
• The optimum pH of the enzyme is 5.8
  
• The enzyme’s activity increases as pH increases 5.0 to 9.0
  
• The enzyme’s activity is greater around pH of 8.0 .
  

Which of the following correctly describes enzyme structure and function?

• The shape of an enzyme is responsible for its function.

• All enzymes can bind to all substrates.

• The substrate is responsible for the shape of the enzyme.

• The location of an enzyme determines its function.

The process of breaking down large molecules

• Anabolism
• Catabolism
• Dehydration
• Synthesis

Catabolic pathways

• Supply energy for cells
• Are endergonic
• Don't need enzymes

Zinc and Iron

• Coenzymes
• Cofactors
• Organic

Blocking Active site of an enzyme

• competitive inhibition
• allosteric inhibition

Succinate dehydrogenase catalyzes the conversion of succinate to fumarate. The reaction is inhibited by malonic acid, which resembles succinate but cannot be acted upon by succinate dehydrogenase. Increasing the ratio of succinate to malonic acid reduces the inhibitory effect of malonic acid. What is malonic acid's role with respect to succinate dehydrogenase?

• It is a competitive inhibitor.
• It is an allosteric regulator.
• It is able to bind to succinate.
• It blocks the binding of fumarate.

An allosteric inhibitor does which of the following?

• Binds to an enzyme away from the active site and changes the conformation of the active site, increasing its affinity for substrate binding

• Binds to the active site and blocks it from binding substrate

• Binds to an enzyme away from the active site and changes the conformation of the active site, decreasing its affinity for the substrate

• Binds directly to the active site and mimics the substrate