Biol211 Chapter 12

Before DNA synthesis, how many chromatids are found per one chromosome?

• 1
• 2
• 3
• 4
• 0

In what part of the cell cycle would you see a condensed chromosome with 2 sister chromatids?

• G1
• G2
• M
• S

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When do sister chromatids split during mitosis?

• Prophase
• Prometaphase
• Metaphase
• Anaphase
• Telophase

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Which best describes the kinetochore?

• a structure composed of several proteins that associate with the centromere region of a chromosome and that can bind to spindle microtubules
• the centromere region of a metaphase chromosome where the DNA can bind with spindle proteins
• the array of vesicles that will form between two dividing nuclei and give rise to the metaphase plate
• the ring of actin microfilaments that will cause the appearance of the cleavage furrow
• the core of proteins that forms the cell plate in a dividing plant cell

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Which statement about typical eukaryotic chromosomes just before and after M phase is incorrect?

• These chromosomes are not in a fully condensed state
• Both contain double-stranded DNA molecules
• Both have one kinetochore structure associated with their centromere
• Both have many proteins associated with the chromosomal DNA
• Typically, both are linear structures with distinct ends

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Which event will likely occur next in a eukaryotic cell entering prometaphase?

• The chromosome material will condense
• Chromosomes will be moved toward alignment at the metaphase plate
• Kinetochores will link some microtubules to the centromeres
• The nuclear membranes will fragment into vesicles
• Microtubules will elongate into the nuclear space

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Which statement comparing cancer cells and normal somatic cells would lose points on a test?

• Cancer cells often deactivate their apoptosis systems
• Cancer cells are not as sensitive to contact inhibition
• The cell cycle often proceeds faster in cancer cells
• Cancer cells are more mobile and less dependent on anchorage
• Cancer cells have more effective DNA repair activities

If you were given a slide and told that the cells on it were performing cytokinesis, how would you tell if they were plant or animal cells?

• Look for a cell plate or a cleavage furrow
• Look for condensed or decondensed chromosomes
• Look for an intact or dispersed nuclear membrane
• Look for more or less layers in the cell wall

Which comes immediately after S phase in the cell cycle?

• G1
• G2
• Mitosis
• Cytokinesis

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Imagine a cell that had 2 copies of each chromosome and had problems with the spindle that caused the sister chromatids to remain attached to each other and to only one spindle pole. What cells would result?

• Both daughter cells have 2 copies of each chromosome
• One daughter cell has 3 copies of each chromosome and one daughter cell with 1 copy of each chromosome
• One daughter cell with 6 copies of each chromosome and one daughter cell with 2 copies of each chromosome
• One daughter cell with 4 copies of each chromosome and one daughter cell with 0 copies of each chromosome
• Both daughter cells have 1 copy of each chromosome

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