Scientists, Enzymes and Proteins - DNA and Protein Synthesis

Determined that transformation occurred when living r cells took up transforming substance from heat killed s cells

• Hershey and Chase

• Griffith

• Watson and Crick

• Franklin

Determined that DNA not protein was the genetic material

• Hershey and Chase

• Watson and Crick

• Chargaff

• Franklin

Took x-ray diffraction photo of DNA

• Franklin

• Watson and Crick

• Chargaff

• Hershey and Chase

Created a model of DNA and got a Nobel Prize

• Franklin

• Chargaff

• Hershey and Chase

• Watson and Crick

Enzyme that unwinds and separates the DNA strand

• DNA polymerase

• primase

• helicase

• topoisomerase

Enzyme that synthesizes the new DNA strand by adding nucleotides

• DNA polymerase

• helicase

• topoisomerase

• primase

Connects DNA fragments on the lagging strand

• helicase

• topoisomerase

• primase

• ligase

Synthesizes short RNA fragments that serve as start sites for replication

• ligase

• helicase

• primase

• DNA polymerase

Removes primers and replaces them with DNA

• helicase

• primase

• ligase

• DNA polymerase

Enzyme that prevents super-coiling of DNA

• helicase

• topoisomerase

• primase

• ligase