Gene Mutations

1. Silent mutations: a. Are a type of point mutation

• Are a type of point mutation

• Code for the same amino acid as intended by the original sequence

• Always affect protein structure and function

• Are a type of point mutation & Code for the same amino acid as intended by the original sequence

• All of the above

2. A frameshift mutation:

• Involves the addition or deletion of one or more nucleotides

• Results in a new codon sequence

• Results in a new amino acid sequence

• All of the above

3. If the DNA sequence “AUGGGACCUCCU” was changed to “AUGGGAAACCUCCU” this would result in:

• A point mutation

• A silent mutation

• A frameshift mutation

4. A geneticist found that a particular mutation had no effect on the polypeptide encoded by a gene. This mutation probably involved:

• Deletion of one nucleotide

• Alteration of the start codon

• Insertion of one nucleotide

• Substitution of one nucleotide

5. Sickle cell results from what type of mutation?

a. Base insertion

• Base insertion

• Base deleted

• Nonsense

• Missense

• Silent