Biology 4.3: Mutations

Which of the following describes a chromosomal duplication mutation?

• A segment of a chromosome is copied twice in a row onto the same chromosome.

• A segment of a chromosome detaches and moves to a non-homologous chromosome.

• A segment of a chromosome is removed.

• A segment of a chromosome is flipped around and copied in the wrong order.

Tags

NGSS.HS-LS3-2

Which of the following describes a chromosomal translocation mutation?

• A segment of a chromosome is copied twice in a row onto the same chromosome.

• A segment of a chromosome detaches and moves to a non-homologous chromosome.

• A segment of a chromosome is removed.

• A segment of a chromosome is flipped around and copied in the wrong order.

Tags

NGSS.HS-LS3-2

If an original sequence of DNA is:

AAC, TCT, GGG, CTA, TCA

Which of the following mutated sequences could result in a frameshift?

• AAC, GGG, CTA, TCA

• CAC, TCT, GGG, CTA, TCA

• AAC, TT, GGG, CTA, TCA

• AAC, TCT, GGG, CAA, TCA

Tags

NGSS.HS-LS3-2

If the original DNA sequence is:

TTTAAACCCGGG

and it is mutated to:

TTTACAACCCGGG

What type of mutation has occurred?

• deletion, frameshift

• insertion, frameshift

• substitution, silent

• substitution, problem

Tags

NGSS.HS-LS3-2

Which of the following genetic problems could cause a person to produce a defective protein?

• a mutation that alters the sequence of nitrogenous bases in their DNA

• a mutation that alters the sequence of the phosphate groups in their DNA

• a mutation that alters the sequence of mRNAs in their amino acids

• a mutation that alters the sequence of tRNAs in their amino acids

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2

Select the THREE causes of genetic mutations:

• viruses

• chemicals and radiation

• errors in DNA replication

• traumatic brain injury

Tags

NGSS.HS-LS3-2

NGSS.HS-LS4-2

Mutations that occur during DNA replication take place in which organelle?

• cell wall

• mitochondria

• ribosome

• nucleus

Tags

NGSS.HS-LS3-2

Original DNA sequence:

TAC, TTT, GAG, CCC

Mutation DNA sequence:

TAC, TTT, CAG, CCC

Which of the following amino acid sequences will be generated by the mutated DNA during translation?

• Met - Lys - Leu - Gly

• Met - Lys - Val - Gly

• Met - Ala - Asp - Leu

• Met - Ala - Ser - Leu

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2

Original DNA:

CCC

Mutated DNA:

CCT

Will this mutation cause a change in the phenotype?

• Yes, because the mutation changes the amino acid.

• Yes, because all mutations changes the phenotype.

• No, because a single substitution cannot affect the phenotype.

• No, because the mutation did not change the amino acid.

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2

Original DNA:

GGG

Mutated DNA:

GTG

Will this mutation cause a change in the phenotype?

• Yes, because the mutation changes the amino acid.

• Yes, because all mutations changes the phenotype.

• No, because a single substitution cannot affect the phenotype.

• No, because the mutation did not change the amino acid.

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2