Friability, Thickness, and Diameter Testing

It is the tendency for a tablet to chip, crumble, or break following compression

• Thickness Testing

• Friability

• Friability Testing

• Diameter Testing

Roche friabilator tester consists of a plastic chamber that revolves at _____ rpm, dropping the tablets through a distance of six inches in the friabilator, which then operate for ____ revolutions.

• 100 rpm; 25 revolutions

• 25 rpm; 100 revolutions

• 50 rpm, 100 revolutions

• None of the above

The following statements are the importance of friability test except

• Measurement of tablet friability supplements other physical strength measurements, such as tablet crushing strength.

• Friability is important since it affects in particle size distribution of granules affecting compressibility into tablet, tablet weight variation, granule flowability.

• In order to monitor the resistance of tablets to such stress and to decide on their suitability for further processing such as coating, tablets are routinely subjected to friability test

• None of the above

Thickness of the tablet is directly proportional to hardness

• FALSE

• TRUE

What is the specification for tablet thickness?

• +/-0.005%

• +/-0.5%

• +/-5%

• 5%

More than 12.50mm, the deviation should not exceed ±5%

• TRUE

• FALSE

The WHT 3ME instrument is designed to automatically measure the four parameters which are:

• Weight

• Height

• Diameter

• Hardness

• Thickness

Effervescent and enteric coated tablet requires uniformity of diameter

• TRUE

• FALSE

All tablets are applicable to uniformity of diameter

• TRUE

• FALSE

Diameter is important for the consistency of the appearance of tablet

• FALSE

• TRUE