Pharm. Chapter 2

A drug that binds to a receptor, and produces a stimulatory response that is similar to what an endogenous substance would have done if it were bound to the receptor is known as a(n):

• receptor

• agonist

• antagonist

• agonist-antagonist

A drug's potency does NOT indicate anything about which of the following?

• tolerance

• target molecules

• affinity

• maximal efficacy

Competitive antagonists are also referred to as:

• surmountable antagonists

• insurmountable antagonists

• agonist-antagonists

• partial agonists

The affinity for a target receptor is its:

• transcription factor

• enzyme activation

• target molecule

• attractive force

The amount of medication needed to produce a specific response in 50% of patients is called the:

• frequency distribution curve

• median effective dose

• maximal efficacy drug

• dose-effect relationship

The pharmacologic actions of a drug that determine its therapeutic effects are called:

• pharmacology

• pharmacokinetics

• pharmacognosy

• pharmacodynamics

Where are intracellular receptors located?

• in the mitochondrion

• in the cytoplasm

• in the nucleus

• in the ribosomes

Which of the following are NOT triggers of second-messenger events?

• B-complex vitamins

• Retinoids

• Steroid agents

• Hormones

Which of the following body fluids is the most commonly used to characterize pharmacologic drug actions?

• Urine

• Cerebrospinal fluid

• Blood

• Sputum

Which of the following in an enzyme embedded in cell membranes?

• insulin

• acetylcholine

• gamma-aminobutyric acid

• serotonin