PT716A_Day2_Gourab Kolay_108_Pilot Plant Scale Up Technique

which of the following areas are fall under the 'space requirement' in pilot plant scale up techniques?

• Administration and Information processing Area

• Physical Testing Area

• Standard Equipment Floor Space

• Storage Area

Same areas should provided for the storage of the in-process materials, finished bulk products from the pilot-plant & materials from the experimental scale-up batches made in the production.

• True

• False

purpose/responsibility of the pilot-plant is (a)   .

which of the following statements is/are false about equipment?

• The most economical and the simplest & efficient equipment which are capable of producing product within the proposed specifications are used

• The size of the equipment should be such that the experimental trials run should be relevant to the production sized batches

• If the equipment is too small the process developed will scale up.

• if equipment is too big then the wastage of the expensive active ingredients occurs.

According to Pilot Plant scale Up Technique, what Is/are the following aspect of Master Manufacturing Procedures?

• Weight Sheet

• Processing Direction

• Manufacturing Procedures

• All of the above option are the aspects

which are the following factors that should be examined during the Process Evaluation Studies under Pilot Plant Scale Up Techniques?

• Mixing Speed and Time

• Rate of addition of granulating agents and solvents

• heating and cooling rates,filter sizes,screen sizes

• drying temperature,drying time

each pilot batch representing the final formulation and manufacturing procedure should be studied for (a)   .

The primary objective of the pilot plant is the physical as well as chemical stability of the products.

• true

• false

The knowledge of the effects of various process parameters are the basis for -

• process optimization

• validation

This area should provide permanent (a)   for routinely used physical- testing equipment.