CHM360 Ch6 Protein Terminology

Molecule bound reversibly by a protein such as a receptor

• Ligand

• Substrate

Site on protein that is complimentary and specific for the ligand

• Active site

• Binding site

Example of how protein-ligand binding increases the complementarity

• Induced fit

• Lock and key

Molecule acted upon by an enzyme

• Ligand

• Substrate

Site on an enzyme that is complementary to the substrate

• Active site

• Binding site