Pathogenesis of Inflammation Quiz

The following mediators are derived from phospholipids of cell membranes EXCEPT:

• histamine

• leukotriene

• prostaglandin

• thromboxane

Vasodilation of blood vessels typically leads to hyperemia.

• True

• False

What is RUBOR, one of the cardinal signs of inflammation?

• swelling

• redness

• warmth/heat

• pain

______ describes the movement of leukocytes toward an injured site due to the presence of certain chemical substances.

• chemotaxis

• opsonization

• anaphylaxis

• agglutination

Which of the following mediators is INCORRECTLY PAIRED with its function?

• bradykinin : increased mucus secretion

• thromboxane : decreased platelet aggregation

• histamine : increased smooth muscle contraction in respiratory tract

• leukotriene: enhanced chemotaxis

________ is the process in which RBCs are stuck together in a single file to form clot due to stagnant blood flow.

• Opsonization

• Pavementing

• Rouleaux

• Chemotaxis

The following occurrences contribute to the increase in vascular permeability EXCEPT ____

• endothelial cell death due to congestion

• beginning of migration of leukocytes out of circulation

• decreased release of toxic mediators at the injured site

• increased pressure due hyperemia.

Complement proteins can function as _________ to increase secretion of histamine from mast cells.

• pyrogens

• chemotactic factors

• opsonins

• anaphylatoxins

Proteins and cells that move from blood to the surrounding tissue outside the main circulation form a/an ________.

• edema

• opsonin

• hyperemia

• MAC

Contraction of the endothelial cells will lead to ______

• pavementing of neutrophils

• more gaps created for blood content to escape from blood vessels out into the tissue

• better opsonization of pathogens for phagocytosis by phagocytes.

• the formation of membrane attack complex.