OTW PART III (industri)
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1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
seorang apt. membuat sediaan suspensi ketoprofen. senyawa ketoprofen memiliki log p 3.2 dan kelarutan dalam air sebesar 51 mg/L. apoteker menambahkan suspending agent kedalam mortir, dan diaduk hingga caira mengembang & terbentuk gelembung udara.
apa fenomena yg terjadi?????
tegangan antar muka antara air dan ketoprofen tinggi
tegangan permukaan antara air dan ketoprofen tinggi
tegangan antar muka antara air dan ketoprofen rendah
tegangan permukaan antara air dan ketoprofen rendah
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
dari data kelarutan, diketahui suatu zat aktif obt A tdk larut dalam air. untuk membuat sediaan dari zat aktif A tsb. formulator menambahkan PEG sehingga kelarutan meningkat.
apakah fungsi PEG dalam sedian tsb??
surfaktan
preserfative
kosolven
pengawet
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
industri farmasi mengembangkan sediaan emulsi parafin liquidum. pada sedian tsb dilakukan uji penentuan kadar ukuran droplet. dari hasil tsb diketahui terjadi peningkatan ukuran dropet per satuan waktu.
apa nama fenomena tersebut...?
coalescence
creaming
flocculation
phase inversiont
ostwald
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
industri farmasi pengembangan o apakah apakahbat dengan sistem vesikel dengan eksipien fosfatidilkolin 2%, etanol 30% & air.
disebut apakah sistemtsb..
liposom
niosom
etosom
tranfersom
fitosom
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
uji volume terpindahkan pd suspensi 50 mg/5mlsebanyak 60 ml pd 10 wadah. hasilnya tdk kurang dari 100%, namun 1 wadah kurangdari 95%.
langkah selanjutnya..
release
reject
menguji 5 wadah lgi
menguji 10 wadah lgi
menguji 20 wadah lgi
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
vitamin c akan dibuat sediaan inj. tanpa penambahan bahan tambahan. metode sterilisasi apa yg tepat, pas dan mantap untuk sediaan tsb..???
panas basah
panas kering
penyinaran
penyaringan
plasma
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
seorang apt RnD diminta untuk melakukan uji disolusi suspensi ibuprofen, dengan alat tipe 2.
basket
keranjang
dayung
floow thhrought cell
recipocrating
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